Impact Factor 2.033
Original research
In Parkinson’s disease (PD), cerebral dopamine depletion is associated with PD subtype-specific metabolic patterns of hypo- and hypermetabolism. It has been hypothesised that hypometabolism reflects impairment...
EJNMMI Research 2017 7:68
Published on: 23 August 2017
Original research
Reference tissue-based quantification of brain PET data does not typically include correction for signal originating from blood vessels, which is known to result in biased outcome measures. The bias extent dep...
EJNMMI Research 2017 7:66
Published on: 18 August 2017
Preliminary research
Cardiac sarcoidosis is associated with major adverse cardiac events including cardiac arrest, for which anti-inflammatory treatment is indicated. Oral corticosteroid is the mainstay among treatment options; ho...
EJNMMI Research 2017 7:67
Published on: 18 August 2017
Original research
Intraoperative sentinel node (SN) identification in patients with head-and-neck malignancies can be challenging due to unexpected drainage patterns and anatomical complexity. Here, intraoperative navigation-ba...
EJNMMI Research 2017 7:65
Published on: 17 August 2017
Original research
α-Amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptor is a primary mediator of fast glutamatergic excitatory signaling in the brain and has been implicated in diverse neuropsychiatric diseases. We ...
EJNMMI Research 2017 7:63
Published on: 16 August 2017
Original research
PET using O-(2-[18F]fluoroethyl)-l-tyrosine (18F-FET) is an established method for brain tumour diagnostics, but data processing varies in different centres. This study analyses the influence of methodological di...
EJNMMI Research 2017 7:64
Published on: 16 August 2017
Original research
The purpose of this study was to develop a positron emission tomography (PET) imaging probe that is easy to synthesize and selectively targets melanoma in vivo. Herein, we report the synthesis and preclinical ...
EJNMMI Research 2017 7:61
Published on: 8 August 2017
Original research
Measures of tumour heterogeneity derived from 18-fluoro-2-deoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) scans are increasingly reported as potential biomarkers of non-small cell l...
EJNMMI Research 2017 7:60
Published on: 26 July 2017
Preliminary research
The 18-kDa translocator protein (TSPO) is an important target for assessing neuroimmune function in brain with positron-emission tomography (PET) imaging. The goal of this work was to assess two [11C]PBR28 imagin...
EJNMMI Research 2017 7:59
Published on: 24 July 2017
Short communication
Kinetic modelling with metabolite-corrected arterial plasma is considered the gold standard for quantification of [11C]PBR28 binding to the translocator protein (TSPO), since there is no brain region devoid of TS...
EJNMMI Research 2017 7:58
Published on: 21 July 2017
Original research
Studies combining immune checkpoint inhibitors with external beam radiation have shown a therapeutic advantage over each modality alone. The purpose of these works is to evaluate the potential of targeted deli...
EJNMMI Research 2017 7:57
Published on: 18 July 2017
Original research
Fluoro-L-thymidine (FLT) is a positron emission tomography/computed tomography (PET/CT) tracer which reflects proliferative activity in a cancer lesion. The main objective of this prospective explorative study...
EJNMMI Research 2017 7:56
Published on: 10 July 2017
Erratum
EJNMMI Research 2017 7:55
Published on: 21 June 2017
The original article was published in EJNMMI Research 2017 7:25
Preliminary Research
Although quantitative analysis using standardized uptake value (SUV) becomes realistic in clinical single-photon emission computed tomography/computed tomography (SPECT/CT) imaging, reconstruction parameter se...
EJNMMI Research 2017 7:53
Published on: 20 June 2017
Original research
[11C]-l-deprenyl-D2 is a positron emission tomography (PET) radioligand for measurement of the monoamine oxidase B (MAO-B) activity in vivo brain. The estimation of the test-retest reproducibility is important fo...
EJNMMI Research 2017 7:54
Published on: 20 June 2017
Original research
The quantification of myocardial blood flow (MBF) and coronary flow reserve (CFR) are useful approaches for evaluating the functional severity of coronary artery disease (CAD). 15O-water positron emission tomogra...
EJNMMI Research 2017 7:52
Published on: 5 June 2017
Short communication
CXCR4 belongs to the family of chemokine receptors. Together with its sole known ligand CXCL12 (SDF-1alpha), it has a pivotal role during organogenesis and for homing of hematopoietic stem cells. CXCR4 is over...
EJNMMI Research 2017 7:51
Published on: 2 June 2017
Original research
We investigated the relationship between metabolic activity and histological features of gliomas using fluorine-18α-methyltyrosine (18F-FAMT) positron emission tomography (PET) compared with fluorine-18 fluorodeo...
EJNMMI Research 2017 7:50
Published on: 31 May 2017
Original research
The ability to image vascular endothelial growth factor (VEGF) could enable prospective, non-invasive monitoring of patients receiving anti-angiogenic therapy. This study investigates the specificity and pharm...
EJNMMI Research 2017 7:49
Published on: 30 May 2017
Original research
PET with O-(2-18F-fluoroethyl)-L-tyrosine (18F-FET) has reached increasing clinical significance for patients with brain neoplasms. For quantification of standard PET-derived parameters such as the tumor-to-backg...
EJNMMI Research 2017 7:48
Published on: 30 May 2017
Original research
An inflammatory reaction in the airways and lung parenchyma, comprised mainly of neutrophils and alveolar macrophages, is present in some patients with chronic obstructive pulmonary disease (COPD). Thoracic fl...
EJNMMI Research 2017 7:47
Published on: 25 May 2017
Original Research
The aim of this study was to investigate the relationship between absorbed dose and response of colorectal cancer liver metastases treated with [90Y]-resin microspheres and to explore possible clinical and imagin...
EJNMMI Research 2017 7:46
Published on: 23 May 2017
Original research
Tumor to normal tissue ratio (T/N ratio) on 11C-methionine (11C-MET) positron emission tomography/computed tomography (PET/CT) is affected by variable factors. We investigated whether T/N ratio cutoff values corr...
EJNMMI Research 2017 7:45
Published on: 23 May 2017
Letter to Editor
This letter is meant to make scientists aware of the proper application of transmission electron microscopy (TEM) for the assessment of polymeric self-assemblies. Cryogenic (cryo)-TEM should be the method of c...
EJNMMI Research 2017 7:44
Published on: 22 May 2017
Original research
Integrin-targeting radiopharmaceuticals have potential broad applications, spanning from cancer theranostics to cardiovascular diseases. We have previously reported preclinical dosimetry results of 68Ga-NODAGA-RG...
EJNMMI Research 2017 7:43
Published on: 18 May 2017
