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EJNMMI Research
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Page 4 of 16

  1. The folate receptor α (FRα)-targeting antibody-drug conjugate (ADC), IMGN853, shows great antitumor activity against FRα-expressing tumors in vivo, but patient selection and consequently therapy outcome are ba...

    Authors: Christian Brand, Ahmad Sadique, Jacob L. Houghton, Kishore Gangangari, Jose F. Ponte, Jason S. Lewis, Naga Vara Kishore Pillarsetty, Jason A. Konner and Thomas Reiner

    Citation: EJNMMI Research 2018 8:87

    Content type: Original research

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  2. A radiomic approach was applied in 18F-FDG PET endometrial cancer, to investigate if imaging features computed on the primary tumour could improve sensitivity in nodal metastases detection. One hundred fifteen...

    Authors: Elisabetta De Bernardi, Alessandro Buda, Luca Guerra, Debora Vicini, Federica Elisei, Claudio Landoni, Robert Fruscio, Cristina Messa and Cinzia Crivellaro

    Citation: EJNMMI Research 2018 8:86

    Content type: Original research

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  3. The InSPira HD system, a novel brain-dedicated SPECT scanner, allows for imaging with a high spatial resolution. Here, we tested whether this scanner can be used to image the dopamine transporter adequately. T...

    Authors: Sofie M. Adriaanse, Tim C. de Wit, Mette Stam, Eline Verwer, Kora M. de Bruin and Jan Booij

    Citation: EJNMMI Research 2018 8:85

    Content type: Short communication

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  4. Several radiolabeled prostate-specific membrane antigen (PSMA) inhibitors based on the lysine-urea-glutamate (KuE) motif as the pharmacophore proved to be suitable tools for PET/SPECT imaging of the PSMA expre...

    Authors: Martina Wirtz, Alexander Schmidt, Margret Schottelius, Stephanie Robu, Thomas Günther, Markus Schwaiger and Hans-Jürgen Wester

    Citation: EJNMMI Research 2018 8:84

    Content type: Original research

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  5. Recent developments in hardware and software for PET technologies have resulted in wide variations in basic performance. Multicentre studies require a standard imaging protocol and SUV harmonization to reduce ...

    Authors: Yuji Tsutsui, Hiromitsu Daisaki, Go Akamatsu, Takuro Umeda, Matsuyoshi Ogawa, Hironori Kajiwara, Shigeto Kawase, Minoru Sakurai, Hiroyuki Nishida, Keiichi Magota, Kazuaki Mori and Masayuki Sasaki

    Citation: EJNMMI Research 2018 8:83

    Content type: Original research

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  6. Programmed cell death 1 (PD-1) inhibitors act as immune checkpoint inhibitors and are more effective for improving survival time with less toxicity as compared with conventional chemotherapies. In anti PD-1 th...

    Authors: Mayu Tomita, Hironobu Yasui, Kei Higashikawa, Kohei Nakajima, Hideo Takakura, Tohru Shiga, Yuji Kuge and Mikako Ogawa

    Citation: EJNMMI Research 2018 8:82

    Content type: Original research

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  7. Erlotinib is an epidermal growth factor receptor (EGFR)-targeting tyrosine kinase inhibitor approved for treatment of non-small cell lung cancer. The wide inter-individual pharmacokinetic (PK) variability of e...

    Authors: Dorra Amor, Sébastien Goutal, Solène Marie, Fabien Caillé, Martin Bauer, Oliver Langer, Sylvain Auvity and Nicolas Tournier

    Citation: EJNMMI Research 2018 8:81

    Content type: Original research

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  8. [18F]Fluoro-2-deoxy-2-d-glucose positron emission tomography (FDG-PET) is commonly used in the clinic for diagnosis of cancer and for follow-up of therapy outcome. Additional to the well-established value in tumo...

    Authors: Stefanie Pektor, Lina Hilscher, Kerstin C. Walzer, Isabelle Miederer, Nicole Bausbacher, Carmen Loquai, Mathias Schreckenberger, Ugur Sahin, Mustafa Diken and Matthias Miederer

    Citation: EJNMMI Research 2018 8:80

    Content type: Original research

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  9. Off-target binding in the choroid plexus (CP) may cause spill-in of the tau PET tracer [18F] flortaucipir into the adjacent hippocampus region. The impact of this spill-in on hippocampal uptake was assessed using...

    Authors: Emma E. Wolters, Sandeep S. V. Golla, Tessa Timmers, Rik Ossenkoppele, Chris W. J. van der Weijden, Philip Scheltens, Lothar Schwarte, Robert C. Schuit, Albert D. Windhorst, Frederik Barkhof, Maqsood Yaqub, Adriaan A. Lammertsma, Ronald Boellaard and Bart N. M. van Berckel

    Citation: EJNMMI Research 2018 8:79

    Content type: Short communication

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  10. The recently growing interest in targeted alpha-therapy (TAT) calls for improvement of the labelling chemistry of the corresponding radionuclides. 213BiIII is a short-lived alpha emitter which emits only one alph...

    Authors: Jakub Šimeček, Petr Hermann, Christof Seidl, Frank Bruchertseifer, Alfred Morgenstern, Hans-Jürgen Wester and Johannes Notni

    Citation: EJNMMI Research 2018 8:78

    Content type: Short communication

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  11. Irradiation with α-particles creates densely packed damage tracks along particle trajectories in exposed cells, including complex DNA damage and closely spaced double-strand breaks (DSBs) in hit nuclei. Here, ...

    Authors: Sarah Schumann, Uta Eberlein, Jessica Müller, Harry Scherthan and Michael Lassmann

    Citation: EJNMMI Research 2018 8:77

    Content type: Original research

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  12. The bone marrow (BM) is a main organ at risk in Lu-177-PSMA-617 therapy of prostate cancer and Lu-177-Octreotate therapy of neuroendocrine tumours. BM dosimetry is challenging and time-consuming, as different ...

    Authors: Astrid Gosewisch, Andreas Delker, Sebastian Tattenberg, Harun Ilhan, Andrei Todica, Julia Brosch, Lena Vomacka, Anika Brunegraf, Franz Josef Gildehaus, Sibylle Ziegler, Peter Bartenstein and Guido Böning

    Citation: EJNMMI Research 2018 8:76

    Content type: Original research

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  13. Somatostatin receptor targeting radiopeptides are successfully being used to image, stage, and monitor patients with neuroendocrine tumours. They are exclusively agonists that internalise upon binding to the r...

    Authors: Keelara Abiraj, Samer Ursillo, Maria Luisa Tamma, Svetlana N. Rylova, Beatrice Waser, Edwin C. Constable, Melpomeni Fani, Guillaume P. Nicolas, Jean Claude Reubi and Helmut R. Maecke

    Citation: EJNMMI Research 2018 8:75

    Content type: Original research

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  14. The D1-dopamine receptor radioligand [11C]SCH23390 has been frequently used in PET studies. In drug-naïve patients with schizophrenia, the findings have been inconsistent, with decreases, increases, and no change...

    Authors: Per Stenkrona, Granville J. Matheson, Simon Cervenka, Pontus Plavén Sigray, Christer Halldin and Lars Farde

    Citation: EJNMMI Research 2018 8:74

    Content type: Original research

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  15. To determine the relative abilities of compartment models to describe time-courses of 18F-fluoromisonidazole (FMISO) tumor uptake in patients with advanced stage non-small cell lung cancer (NSCLC) imaged using...

    Authors: Daniel R. McGowan, Michael Skwarski, Bartlomiej W. Papiez, Ruth E. Macpherson, Fergus V. Gleeson, Julia A. Schnabel, Geoff S. Higgins and John D. Fenwick

    Citation: EJNMMI Research 2018 8:73

    Content type: Original research

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  16. This study identified the optimal tracer kinetic model for quantification of dynamic O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET) positron emission tomography (PET) studies in seven patients with diffuse glioma (...

    Authors: Thomas Koopman, Niels Verburg, Robert C. Schuit, Petra J. W. Pouwels, Pieter Wesseling, Albert D. Windhorst, Otto S. Hoekstra, Philip C. de Witt Hamer, Adriaan A. Lammertsma, Ronald Boellaard and Maqsood Yaqub

    Citation: EJNMMI Research 2018 8:72

    Content type: Original research

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  17. We measured whole body distribution of 11C-BU99008, a new PET biomarker for non-invasive identification of the imidazoline2 binding site. The purpose of this phase I study was to evaluate the biodistribution and ...

    Authors: Ashwin V. Venkataraman, Nicholas Keat, James F. Myers, Samuel Turton, Inge Mick, Roger N. Gunn, Eugenii A. Rabiner, Jan Passchier, Christine A. Parker, Robin J. Tyacke and David J. Nutt

    Citation: EJNMMI Research 2018 8:71

    Content type: Original research

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  18. In contrast to ordered subset expectation maximization (OSEM), block sequential regularized expectation maximization (BSREM) positron emission tomography (PET) reconstruction algorithms can run until full conv...

    Authors: Edwin E. G. W. ter Voert, Urs J. Muehlematter, Gaspar Delso, Daniele A. Pizzuto, Julian Müller, Hannes W. Nagel and Irene A. Burger

    Citation: EJNMMI Research 2018 8:70

    Content type: Original research

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  19. Efforts to develop suitable positron emission tomography (PET) tracers for the ion channel site of human N-methyl-d-aspartate (NMDA) receptors have had limited success. [18F]PK-209 is a GMOM derivative that binds...

    Authors: Jasper van der Aart, Sandeep S. V. Golla, Marieke van der Pluijm, Lothar A. Schwarte, Robert C. Schuit, Pieter J. Klein, Athanasios Metaxas, Albert D. Windhorst, Ronald Boellaard, Adriaan A. Lammertsma and Bart N. M. van Berckel

    Citation: EJNMMI Research 2018 8:69

    Content type: Original research

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  20. Unfortunately, after publication of this article [1], it was noticed that the name of Urs J. Muehlematter was incorrectly displayed as Urs J. Mühlematter. The corrected author list can be seen above and the or...

    Authors: Urs J. Muehlematter, Hannes W. Nagel, Anton Becker, Julian Mueller, Kerstin N. Vokinger, Felipe de Galiza Barbosa, Edwin E. G. T. ter Voert, Patrick Veit-Haibach and Irene A. Burger

    Citation: EJNMMI Research 2018 8:68

    Content type: Correction

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    The original article was published in EJNMMI Research 2018 8:41

  21. The ability to accurately and non-invasively distinguish high-grade glioma from low-grade glioma remains a challenge despite advances in molecular and magnetic resonance imaging. We investigated the ability of...

    Authors: Ephraim E. Parent, Marc Benayoun, Ijeoma Ibeanu, Jeffrey J. Olson, Constantinos G. Hadjipanayis, Daniel J. Brat, Vikram Adhikarla, Jonathon Nye, David M. Schuster and Mark M. Goodman

    Citation: EJNMMI Research 2018 8:67

    Content type: Original research

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  22. Florbetaben, a 18F-labeled stilbene derivative (Neuraceq®, formerly known as BAY-949172), is a diagnostic radiopharmaceutical developed to visualize β-amyloid plaques in the brain. Here, we report a pilot study e...

    Authors: Lucia Baratto, Sonya Youngju Park, Negin Hatami, Praveen Gulaka, Shreyas Vasanawala, Thomas Koshy Yohannan, Robert Herfkens, Ronald Witteles and Andrei Iagaru

    Citation: EJNMMI Research 2018 8:66

    Content type: Short communication

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  23. Localizing and removing the infected sequestrum in long-standing trauma-related chronic osteomyelitis remains a clinical challenge. PET/CT with 18F-fluorodeoxyglucose (FDG-PET) has a high sensitivity for chron...

    Authors: Albert Christersson, Sune Larsson and Jens Sörensen

    Citation: EJNMMI Research 2018 8:65

    Content type: Original research

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  24. Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin tumor. Currently, 18F-fluoro-deoxy-glucose (18F-FDG) PET/CT is the functional imaging modality of choice. Few data are available on the use of 68Ga...

    Authors: Silvia Taralli, Martina Sollini, Michele Milella, Germano Perotti, Angelina Filice, Massimo Menga, Annibale Versari and Vittoria Rufini

    Citation: EJNMMI Research 2018 8:64

    Content type: Original research

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  25. Graphical methods of radiotracer kinetic modeling in PET are ideal for parametric imaging and data quality assurance but can suffer from noise bias. This study compared the Logan and Multilinear Analysis-1 (MA...

    Authors: Tong Wang, Kai Yi Wu, Robert C. Miner, Jennifer M. Renaud, Rob S. B. Beanlands and Robert A. deKemp

    Citation: EJNMMI Research 2018 8:63

    Content type: Original research

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  26. The 18F-THK-5351 radiotracer has been used to detect the in vivo tau protein distribution in patients with tauopathy, such as Alzheimer’s disease and corticobasal syndrome. In addition, 18F-THK-5351 can also moni...

    Authors: Kuo-Lun Huang, Jung-Lung Hsu, Kun-Ju Lin, Chien-Hung Chang, Yi-Ming Wu, Ting-Yu Chang, Yeu-Jhy Chang, Chi-Hung Liu, Meng-Yang Ho, Shiaw-Pyng Wey, Tzu-Chen Yen, Nobuyuki Okamura, Ing-Tsung Hsiao and Tsong-Hai Lee

    Citation: EJNMMI Research 2018 8:62

    Content type: Original research

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  27. Nonalcoholic fatty liver disease is a common disorder that progresses from simple fatty liver (steatosis) to nonalcoholic steatohepatitis (NASH). It is thought that mitochondrial dysfunction plays a critical r...

    Authors: Toshihiro Sakai, Hiroyuki Ohba, Shingo Nishiyama, Takeharu Kakiuchi, Osamu Inoue and Hideo Tsukada

    Citation: EJNMMI Research 2018 8:61

    Content type: Original research

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  28. The aim of this work was to confirm that post-selective internal radiation therapy (SIRT) 90Y-PET/CT-based dosimetry correlates with lesion metabolic response and to determine its correlation with overall surviva...

    Authors: Hugo Levillain, Ivan Duran Derijckere, Gwennaëlle Marin, Thomas Guiot, Michaël Vouche, Nick Reynaert, Alain Hendlisz, Bruno Vanderlinden and Patrick Flamen

    Citation: EJNMMI Research 2018 8:60

    Content type: Original research

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  29. Radiation injury can be indistinguishable from recurrent tumor on standard imaging. Current protocols for this differential diagnosis require one or more follow-up imaging studies, long dynamic acquisitions, o...

    Authors: Patrick L. Donabedian, Susanne Kossatz, John A. Engelbach, Stephen A. Jannetti, Brandon Carney, Robert J. Young, Wolfgang A. Weber, Joel R. Garbow and Thomas Reiner

    Citation: EJNMMI Research 2018 8:59

    Content type: Original research

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  30. Kinetic analysis of dynamic PET data requires an accurate knowledge of available PET tracer concentration within blood plasma over time, known as the arterial input function (AIF). The gold standard method use...

    Authors: Hasan Sari, Kjell Erlandsson, Lisbeth Marner, Ian Law, Henrik B.W. Larsson, Kris Thielemans, Sébastien Ourselin, Simon Arridge, David Atkinson and Brian F. Hutton

    Citation: EJNMMI Research 2018 8:58

    Content type: Original research

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  31. Inflammation is associated with major depressive disorder (MDD). Translocator protein 18 kDa (TSPO), a putative biomarker of neuroinflammation, is quantified using positron emission tomography (PET) and 11C-PBR28...

    Authors: Erica M. Richards, Paolo Zanotti-Fregonara, Masahiro Fujita, Laura Newman, Cristan Farmer, Elizabeth D. Ballard, Rodrigo Machado-Vieira, Peixiong Yuan, Mark J. Niciu, Chul Hyoung Lyoo, Ioline D. Henter, Giacomo Salvadore, Wayne C. Drevets, Hartmuth Kolb, Robert B. Innis and Carlos A. Zarate Jr

    Citation: EJNMMI Research 2018 8:57

    Content type: Original research

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  32. External cooling of the salivary glands is advised to prevent xerostomia in lutetium-177-PSMA treatment for advanced prostate cancer. Since evidence addressing this subject is sparse, this study aims to determ...

    Authors: Ludwike W. M. van Kalmthout, Marnix G. E. H. Lam, Bart de Keizer, Gerard C. Krijger, Tessa F. T. Ververs, Rememrt de Roos and Arthur J. A. T. Braat

    Citation: EJNMMI Research 2018 8:56

    Content type: Original research

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  33. There is a growing interest in the use of 18F-FDG PET-CT to monitor tuberculosis (TB) treatment response. However, TB causes complex and widespread pathology, which is challenging to segment and quantify in a rep...

    Authors: Stephanus T. Malherbe, Patrick Dupont, Ilse Kant, Petri Ahlers, Magdalena Kriel, André G. Loxton, Ray Y. Chen, Laura E. Via, Friedrich Thienemann, Robert J. Wilkinson, Clifton E. Barry III, Stephanie Griffith-Richards, Annare Ellman, Katharina Ronacher, Jill Winter, Gerhard Walzl…

    Citation: EJNMMI Research 2018 8:55

    Content type: Original research

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  34. The present study proposed a new concept for targeted radionuclide therapy (TRT) to improve the intratumoral distribution of radioactivity using two different radiopharmaceuticals. We examined the efficacy of ...

    Authors: Zhao-Hui Jin, Atsushi B. Tsuji, Mélissa Degardin, Aya Sugyo, Yukie Yoshii, Kotaro Nagatsu, Ming-Rong Zhang, Yasuhisa Fujibayashi, Pascal Dumy, Didier Boturyn and Tatsuya Higashi

    Citation: EJNMMI Research 2018 8:54

    Content type: Original research

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  35. Quantitative imaging can facilitate patient stratification in clinical trials. The hypoxia-activated prodrug evofosfamide recently failed a phase III trial in pancreatic cancer. However, the study did not atte...

    Authors: Milan Grkovski, Louise Fanchon, Naga Vara Kishore Pillarsetty, James Russell and John L. Humm

    Citation: EJNMMI Research 2018 8:53

    Content type: Short communication

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  36. This study investigated the spatial relationship of 2-deoxy-2-[18F]-fluoro-D-glucose positron emission tomography ([18F]FDG-PET) standardized uptake values (SUVs) and apparent diffusion coefficients (ADCs) derive...

    Authors: John M. Floberg, Kathryn J. Fowler, Dominique Fuser, Todd A. DeWees, Farrokh Dehdashti, Barry A. Siegel, Richard L. Wahl, Julie K. Schwarz and Perry W. Grigsby

    Citation: EJNMMI Research 2018 8:52

    Content type: Original research

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  37. Tracers triggering αvβ3 integrins, such as certain RGD-containing peptides, were found promising in previous pilot studies characterizing high-grade gliomas. However, only limited comparisons have been perform...

    Authors: Sibel Isal, Julien Pierson, Laetitia Imbert, Alexandra Clement, Charlotte Collet, Sophie Pinel, Nicolas Veran, Aurélie Reinhard, Sylvain Poussier, Guillaume Gauchotte, Steeven Frezier, Gilles Karcher, Pierre-Yves Marie and Fatiha Maskali

    Citation: EJNMMI Research 2018 8:51

    Content type: Original research

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  38. A major toxicity concern in radioembolization therapy of hepatic malignancies is radiation-induced pneumonitis and sclerosis due to hepatopulmonary shunting of 90Y microspheres. Currently, 99mTc macroaggregated a...

    Authors: Jonathan D. Allred, Jeremy Niedbala, Justin K. Mikell, Dawn Owen, Kirk A. Frey and Yuni K. Dewaraja

    Citation: EJNMMI Research 2018 8:50

    Content type: Original research

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  39. Suboptimal temporal sampling of time-activity curves (TAC) from dynamic 18F-fluoromethylcholine (FCH) PET images may introduce bias in quantification of FCH uptake in prostate cancer assessment. We sought to defi...

    Authors: Xavier Palard-Novello, Anne-Lise Blin, Florence Le Jeune, Etienne Garin, Pierre-Yves Salaün, Anne Devillers, Giulio Gambarota, Solène Querellou, Patrick Bourguet and Hervé Saint-Jalmes

    Citation: EJNMMI Research 2018 8:49

    Content type: Original research

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  40. The histamine H3 receptor is regarded as a drug target for cognitive impairments in psychiatric disorders. H3 receptors are expressed in neocortical areas, including the prefrontal cortex, the key region of cogni...

    Authors: Takehito Ito, Yasuyuki Kimura, Chie Seki, Masanori Ichise, Keita Yokokawa, Kazunori Kawamura, Hidehiko Takahashi, Makoto Higuchi, Ming-Rong Zhang, Tetsuya Suhara and Makiko Yamada

    Citation: EJNMMI Research 2018 8:48

    Content type: Short communication

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  41. The potential of the D-isomerization of 4-borono-2-18F-fluoro-phenylalanine (18F-FBPA) to improve its target tumor to non-target normal brain tissue ratio (TBR) was evaluated in rat brain glioma and compared with...

    Authors: Masakatsu Kanazawa, Shingo Nishiyama, Fumio Hashimoto, Takeharu Kakiuchi and Hideo Tsukada

    Citation: EJNMMI Research 2018 8:47

    Content type: Original research

    Published on:

  42. The NMDA receptor radiotracer [18F]GE-179 has been used with 90-min scans and arterial plasma input functions. We explored whether (1) arterial blood sampling is avoidable and (2) shorter scans are feasible.

    Authors: Colm J. McGinnity, Daniela A. Riaño Barros, William Trigg, David J. Brooks, Rainer Hinz, John S. Duncan, Matthias J. Koepp and Alexander Hammers

    Citation: EJNMMI Research 2018 8:46

    Content type: Short Communication

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  43. Microvascular function plays an important role in ARVD (atherosclerotic renovascular disease). RFR (renal flow reserve), the capacity of renal vasculature to dilate, is known to reflect renal microvascular fun...

    Authors: Johanna Päivärinta, Niina Koivuviita, Vesa Oikonen, Hidehiro Iida, Kaisa Liukko, Ilkka Manner, Eliisa Löyttyniemi, Pirjo Nuutila and Kaj Metsärinne

    Citation: EJNMMI Research 2018 8:45

    Content type: Original research

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  44. The close connection between neuronal activity and glucose consumption accounts for the clinical value of 18F-fluoro-2-deoxyglucose (FDG) imaging in neurodegenerative disorders. Nevertheless, brain metabolic r...

    Authors: Ambra Buschiazzo, Vanessa Cossu, Matteo Bauckneht, Annamaria Orengo, Patrizia Piccioli, Laura Emionite, Giovanna Bianchi, Federica Grillo, Anna Rocchi, Francesco Di Giulio, Francesco Fiz, Lizzia Raffaghello, Flavio Nobili, Silvia Bruno, Giacomo Caviglia, Silvia Ravera…

    Citation: EJNMMI Research 2018 8:44

    Content type: Original research

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  45. Translocator protein (TSPO) imaging can be used to detect neuroinflammation (including microglial activation) after acute cerebral infarction. However, longitudinal changes of TSPO binding after mild ischemia ...

    Authors: Natsumi Miyajima, Miwa Ito, Takemi Rokugawa, Hitoshi Iimori, Sotaro Momosaki, Shigeki Omachi, Eku Shimosegawa, Jun Hatazawa and Kohji Abe

    Citation: EJNMMI Research 2018 8:43

    Content type: Original research

    Published on:

  46. This study explores various volume of interest (VOI) delineation techniques for fluorine-18-fluorodeoxyglucose positron emission tomography with computed tomography (18F-FDG PET-CT) scans during neoadjuvant extre...

    Authors: Marc G. Stevenson, Lukas B. Been, Harald J. Hoekstra, Albert J. H. Suurmeijer, Ronald Boellaard and Adrienne H. Brouwers

    Citation: EJNMMI Research 2018 8:42

    Content type: Original Research

    Published on:

  47. Accurate attenuation correction (AC) is an inherent problem of positron emission tomography magnetic resonance imaging (PET/MRI) systems. Simulation studies showed that time-of-flight (TOF) detectors can reduc...

    Authors: Urs J. Muehlematter, Hannes W. Nagel, Anton Becker, Julian Mueller, Kerstin N. Vokinger, Felipe de Galiza Barbosa, Edwin E. G. T. ter Voert, Patrick Veit-Haibach and Irene A. Burger

    Citation: EJNMMI Research 2018 8:41

    Content type: Original research

    Published on:

    The Correction to this article has been published in EJNMMI Research 2018 8:68

  48. Activated hepatic stellate cells (HSCs), which express integrin αvβ3, are a major fibrogenic factor in NASH pathophysiology. 18F-labeled cyclic arginine-glycine-aspartic acid penta-peptide (18F-FPP-RGD2) has been...

    Authors: Takemi Rokugawa, Haruyo Konishi, Miwa Ito, Hitoshi Iimori, Ryohei Nagai, Eku Shimosegawa, Jun Hatazawa and Kohji Abe

    Citation: EJNMMI Research 2018 8:40

    Content type: Original Research

    Published on:

  49. The protein cross-linking enzyme tissue transglutaminase (TG2; EC 2.3.2.13) is associated with the pathogenesis of various diseases, including cancer. Recently, the synthesis and initial evaluation of two high...

    Authors: Berend van der Wildt, Micha M. M. Wilhelmus, Wissam Beaino, Esther J. M. Kooijman, Robert C. Schuit, John G. J. M. Bol, John J. P. Breve, Ralf Pasternack, Adriaan A. Lammertsma, Albert D. Windhorst and Benjamin Drukarch

    Citation: EJNMMI Research 2018 8:39

    Content type: Original research

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  50. The current de facto standard for quantification of tumor metabolism in oncological whole-body PET is the standardized uptake value (SUV) approach. SUV determination requires accurate scanner calibration. Resi...

    Authors: Jens Maus, Frank Hofheinz, Ivayla Apostolova, Michael C. Kreissl, Jörg Kotzerke and Jörg van den Hoff

    Citation: EJNMMI Research 2018 8:38

    Content type: Original research

    Published on:

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