Chakraborty PK, Gildersleeve DL, Jewett DM, Toorongian SA, Kilbourn MR, Schwaiger M, Wieland DM: High yield synthesis of high specific activity R-(-)-[11C] epinephrine for routine PET studies in humans. Nucl Med Biol 1993, 20: 939–944. 10.1016/0969-8051(93)90094-B
Article
CAS
PubMed
Google Scholar
Goldstein DS, Chang PC, Eisenhofer G, Miletich R, Finn R, Bacher J, Kirk KL, Bacharach S, Kopin IJ: Positron emission tomographic imaging of cardiac sympathetic innervation and function. Circulation 1990, 81: 1606–1621. 10.1161/01.CIR.81.5.1606
Article
CAS
PubMed
Google Scholar
Munch G, Nguyen NT, Nekolla S, Ziegler S, Muzik O, Chakraborty P, Wieland DM, Schwaiger M: Evaluation of sympathetic nerve terminals with [(11) C] epinephrine and [(11) C] hydroxyephedrine and positron emission tomography. Circulation 2000, 101: 516–523. 10.1161/01.CIR.101.5.516
Article
CAS
PubMed
Google Scholar
Rosenspire KC, Haka MS, Van Dort ME, Jewett DM, Gildersleeve DL, Schwaiger M, Wieland DM: Synthesis and preliminary evaluation of carbon-11-meta-hydroxyephedrine: a false transmitter agent for heart neuronal imaging. J Nucl Med 1990, 31: 1328–1334.
CAS
PubMed
Google Scholar
Schwaiger M, Kalff V, Rosenspire K, Haka MS, Molina E, Hutchins GD, Deeb M, Wolfe E Jr, Wieland DM: Noninvasive evaluation of sympathetic nervous system in human heart by positron emission tomography. Circulation 1990, 82: 457–464. 10.1161/01.CIR.82.2.457
Article
CAS
PubMed
Google Scholar
Dae MW, O'Connell JW, Botvinick EH, Ahearn T, Yee E, Huberty JP, Mori H, Chin MC, Hattner RS, Herre JM: Scintigraphic assessment of regional cardiac adrenergic innervation. Circulation 1989, 79: 634–644. 10.1161/01.CIR.79.3.634
Article
CAS
PubMed
Google Scholar
Kline RC, Swanson DP, Wieland DM, Thrall JH, Gross MD, Pitt B, Beierwaltes WH: Myocardial imaging in man with I-123 meta-iodobenzylguanidine. J Nucl Med 1981, 22: 129–132.
CAS
PubMed
Google Scholar
Wieland DM, Wu J, Brown LE, Mangner TJ, Swanson DP, Beierwaltes WH: Radiolabeled adrenergic neuron-blocking agents: adrenomedullary imaging with [131I] iodobenzylguanidine. J Nucl Med 1980, 21: 349–353.
CAS
PubMed
Google Scholar
Jacobson AF, Senior R, Cerqueira MD, Wong ND, Thomas GS, Lopez VA, Agostini D, Weiland F, Chandna H, Narula J: Myocardial iodine-123 meta-iodobenzylguanidine imaging and cardiac events in heart failure. Results of the prospective ADMIRE-HF (AdreView Myocardial Imaging for Risk Evaluation in Heart Failure) study. J Am Coll Cardiol 2010, 55: 2212–2221. 10.1016/j.jacc.2010.01.014
Article
PubMed
Google Scholar
Paul M, Schafers M, Kies P, Acil T, Schafers K, Breithardt G, Schober O, Wichter T: Impact of sympathetic innervation on recurrent life-threatening arrhythmias in the follow-up of patients with idiopathic ventricular fibrillation. Eur J Nucl Med Mol Imaging 2006, 33: 866–870. 10.1007/s00259-005-0061-7
Article
PubMed
Google Scholar
Yukinaka M, Nomura M, Ito S, Nakaya Y: Mismatch between myocardial accumulation of 123I-MIBG and 99mTc-MIBI and late ventricular potentials in patients after myocardial infarction: association with the development of ventricular arrhythmias. Am Heart J 1998, 136: 859–867. 10.1016/S0002-8703(98)70132-2
Article
CAS
PubMed
Google Scholar
Boogers MJ, Borleffs CJ, Henneman MM, van Bommel RJ, van Ramshorst J, Boersma E, Dibbets-Schneider P, Stokkel MP, van der Wall EE, Schalij MJ, Bax JJ: Cardiac sympathetic denervation assessed with 123-iodine metaiodobenzylguanidine imaging predicts ventricular arrhythmias in implantable cardioverter-defibrillator patients. J Am Coll Cardiol 2010, 55: 2769–2777. 10.1016/j.jacc.2009.12.066
Article
PubMed
Google Scholar
Nishisato K, Hashimoto A, Nakata T, Doi T, Yamamoto H, Nagahara D, Shimoshige S, Yuda S, Tsuchihashi K, Shimamoto K: Impaired cardiac sympathetic innervation and myocardial perfusion are related to lethal arrhythmia: quantification of cardiac tracers in patients with ICDs. J Nucl Med 2010, 51: 1241–1249. 10.2967/jnumed.110.074971
Article
PubMed
Google Scholar
Allman KC, Stevens MJ, Wieland DM, Hutchins GD, Wolfe ER Jr, Greene DA, Schwaiger M: Noninvasive assessment of cardiac diabetic neuropathy by carbon-11 hydroxyephedrine and positron emission tomography. J Am Coll Cardiol 1993, 22: 1425–1432. 10.1016/0735-1097(93)90553-D
Article
CAS
PubMed
Google Scholar
Bengel FM, Barthel P, Matsunari I, Schmidt G, Schwaiger M: Kinetics of 123I-MIBG after acute myocardial infarction and reperfusion therapy. J Nucl Med 1999, 40: 904–910.
CAS
PubMed
Google Scholar
Inoue H, Zipes DP: Results of sympathetic denervation in the canine heart: supersensitivity that may be arrhythmogenic. Circulation 1987, 75: 877–887. 10.1161/01.CIR.75.4.877
Article
CAS
PubMed
Google Scholar
Kammerling JJ, Green FJ, Watanabe AM, Inoue H, Barber MJ, Henry DP, Zipes DP: Denervation supersensitivity of refractoriness in noninfarcted areas apical to transmural myocardial infarction. Circulation 1987, 76: 383–393. 10.1161/01.CIR.76.2.383
Article
CAS
PubMed
Google Scholar
Luisi AJ Jr, Suzuki G, Dekemp R, Haka MS, Toorongian SA, Canty JM Jr, Fallavollita JA: Regional 11C-hydroxyephedrine retention in hibernating myocardium: chronic inhomogeneity of sympathetic innervation in the absence of infarction. J Nucl Med 2005, 46: 1368–1374.
CAS
PubMed
Google Scholar
Matsunari I, Schricke U, Bengel FM, Haase HU, Barthel P, Schmidt G, Nekolla SG, Schoemig A, Schwaiger M: Extent of cardiac sympathetic neuronal damage is determined by the area of ischemia in patients with acute coronary syndromes. Circulation 2000, 101: 2579–2585. 10.1161/01.CIR.101.22.2579
Article
CAS
PubMed
Google Scholar
Schwaiger M, Guibourg H, Rosenspire K, McClanahan T, Gallagher K, Hutchins G, Wieland DM: Effect of regional myocardial ischemia on sympathetic nervous system as assessed by fluorine-18-metaraminol. J Nucl Med 1990, 31: 1352–1357.
CAS
PubMed
Google Scholar
Simoes MV, Barthel P, Matsunari I, Nekolla SG, Schomig A, Schwaiger M, Schmidt G, Bengel FM: Presence of sympathetically denervated but viable myocardium and its electrophysiologic correlates after early revascularised, acute myocardial infarction. Eur Heart J 2004, 25: 551–557. 10.1016/j.ehj.2004.02.016
Article
PubMed
Google Scholar
Sasano T, Abraham MR, Chang KC, Ashikaga H, Mills KJ, Holt DP, Hilton J, Nekolla SG, Dong J, Lardo AC, Halperin H, Dannals RF, Marbán E, Bengel FM: Abnormal sympathetic innervation of viable myocardium and the substrate of ventricular tachycardia after myocardial infarction. J Am Coll Cardiol 2008, 51: 2266–2275. 10.1016/j.jacc.2008.02.062
Article
PubMed
Google Scholar
Fallavollita JA, Banas MD, Suzuki G, de Kemp RA, Sajjad M, Canty JM Jr: 11C-meta-hydroxyephedrine defects persist despite functional improvement in hibernating myocardium. J Nucl Cardiol 2010, 17: 85–96. 10.1007/s12350-009-9164-z
Article
PubMed Central
PubMed
Google Scholar
Hartmann F, Ziegler S, Nekolla S, Hadamitzky M, Seyfarth M, Richardt G, Schwaiger M: Regional patterns of myocardial sympathetic denervation in dilated cardiomyopathy: an analysis using carbon-11 hydroxyephedrine and positron emission tomography. Heart 1999, 81: 262–270.
Article
PubMed Central
CAS
PubMed
Google Scholar
Stevens MJ, Raffel DM, Allman KC, Dayanikli F, Ficaro E, Sandford T, Wieland DM, Pfeifer MA, Schwaiger M: Cardiac sympathetic dysinnervation in diabetes: implications for enhanced cardiovascular risk. Circulation 1998, 98: 961–968. 10.1161/01.CIR.98.10.961
Article
CAS
PubMed
Google Scholar
Rimoldi OE, Drake-Holland AJ, Noble MI, Camici PG: Basal and hyperaemic myocardial blood flow in regionally denervated canine hearts: an in vivo study with positron emission tomography. Eur J Nucl Med Mol Imaging 2007, 34: 197–205. 10.1007/s00259-006-0233-0
Article
PubMed
Google Scholar
Schafers M, Dutka D, Rhodes CG, Lammertsma AA, Hermansen F, Schober O, Camici PG: Myocardial presynaptic and postsynaptic autonomic dysfunction in hypertrophic cardiomyopathy. Circ Res 1998, 82: 57–62. 10.1161/01.RES.82.1.57
Article
CAS
PubMed
Google Scholar
Van Dort ME, Tluczek L: Synthesis and carbon-11 labeling of the stereoisomers of meta -hydroxyephedrine (HED) and meta -hydroxypseudoephedrine (HPED). J Label Compd Radiopharm 2000, 43: 603–612. 10.1002/(SICI)1099-1344(200005)43:6<603::AID-JLCR345>3.0.CO;2-#
Article
CAS
Google Scholar
Surti S, Kuhn A, Werner ME, Perkins AE, Kolthammer J, Karp JS: Performance of Philips Gemini TF PET/CT scanner with special consideration for its time-of-flight imaging capabilities. J Nucl Med 2007, 48: 471–480.
PubMed
Google Scholar
Boellaard R, van Lingen A, van Balen SC, Hoving BG, Lammertsma AA: Characteristics of a new fully programmable blood sampling device for monitoring blood radioactivity during PET. Eur J Nucl Med 2001, 28: 81–89. 10.1007/s002590000405
Article
CAS
PubMed
Google Scholar
Thackeray JT, Beanlands RS, Dasilva JN: Presence of specific 11C-meta-hydroxyephedrine retention in heart, lung, pancreas, and brown adipose tissue. J Nucl Med 2007, 48: 1733–1740. 10.2967/jnumed.107.043570
Article
CAS
PubMed
Google Scholar
van den Hoff J, Burchert W, Muller-Schauenburg W, Meyer GJ, Hundeshagen H: Accurate local blood flow measurements with dynamic PET: fast determination of input function delay and dispersion by multilinear minimization. J Nucl Med 1993, 34: 1770–1777.
CAS
PubMed
Google Scholar
van der Weerdt AP, Klein LJ, Boellaard R, Visser CA, Visser FC, Lammertsma AA: Image-derived input functions for determination of MRGlu in cardiac (18) F-FDG PET scans. J Nucl Med 2001, 42: 1622–1629.
CAS
PubMed
Google Scholar
Lubberink M, Harms HJ, Halbmeijer R, de Haan S, Knaapen P, Lammertsma AA: Low-dose quantitative myocardial blood flow imaging using 15O-water and PET without attenuation correction. J Nucl Med 2010, 51: 575–580. 10.2967/jnumed.109.070748
Article
PubMed
Google Scholar
Gunn RN, Sargent PA, Bench CJ, Rabiner EA, Osman S, Pike VW, Hume SP, Grasby PM, Lammertsma AA: Tracer kinetic modeling of the 5-HT1A receptor ligand [carbonyl-11C] WAY-100635 for PET. Neuroimage 1998, 8: 426–440. 10.1006/nimg.1998.0379
Article
CAS
PubMed
Google Scholar
Cerqueira MD, Weissman NJ, Dilsizian V, Jacobs AK, Kaul S, Laskey WK, Pennell DJ, Rumberger JA, Ryan T, Verani MS: Standardized myocardial segmentation and nomenclature for tomographic imaging of the heart. A statement for healthcare professionals from the Cardiac Imaging Committee of the Council on Clinical Cardiology of the American Heart Association. Int J Cardiovasc Imaging 2002, 18: 539–542.
PubMed
Google Scholar
Lammertsma AA, De SR, Araujo LI, Jones T: Measurement of regional myocardial blood flow using C15O2 and positron emission tomography: comparison of tracer models. Clin Phys Physiol Meas 1992, 13: 1–20. 10.1088/0143-0815/13/1/001
Article
CAS
PubMed
Google Scholar
Innis RB, Cunningham VJ, Delforge J, Fujita M, Gjedde A, Gunn RN, Holden J, Houle S, Huang SC, Ichise M, Iida H, Ito H, Kimura Y, Koeppe RA, Knudsen GM, Knuuti J, Lammertsma AA, Laruelle M, Logan J, Maguire RP, Mintun MA, Morris ED, Parsey R, Price JC, Slifstein M, Sossi V, Suhara T, Votaw JR, Wong DF, Carson RE: Consensus nomenclature for in vivo imaging of reversibly binding radioligands. J Cereb Blood Flow Metab 2007, 27: 1533–1539. 10.1038/sj.jcbfm.9600493
Article
CAS
PubMed
Google Scholar
Akaike H: A new look at the statistical model identification. IEEE T Automat Contr 1974, 19: 716–723. 10.1109/TAC.1974.1100705
Article
Google Scholar
Schwarz G: Estimating the dimension of a model. Ann Statist 1978, 6: 461–464. 10.1214/aos/1176344136
Article
Google Scholar
Crystal GJ, Downey HF, Bashour FA: Small vessel and total coronary blood volume during intracoronary adenosine. Am J Physiol 1981, 241: H194-H201.
CAS
PubMed
Google Scholar
Raffel DM, Koeppe RA, Jung YW, Gu G, Jang KS, Sherman PS, Quesada CA: Quantification of cardiac sympathetic nerve density with N-11C-guanyl-meta-octopamine and tracer kinetic analysis. J Nucl Med 2013, 54: 1645–1652. 10.2967/jnumed.113.120659
Article
CAS
PubMed
Google Scholar
Thackeray JT, de Kemp RA, Beanlands RS, Dasilva JN: Insulin restores myocardial presynaptic sympathetic neuronal integrity in insulin-resistant diabetic rats. J Nucl Cardiol 2013, 20: 845–856. 10.1007/s12350-013-9759-2
Article
PubMed
Google Scholar
Harms HJ, de Haan S, Knaapen P, Huisman MC, Schuit RC, Windhorst AD, Allaart CP, Lammertsma AA, Lubberink M: Tracer kinetic analysis of myocardial [11C] hydroxyephedrine studies [abstract]. J Nucl Med 2011, 52: 254. 10.2967/jnumed.110.085431
Article
Google Scholar
Van der Veldt AAM, Hendrikse NH, Harms HJ, Comans EF, Postmos PE, Smit EF, Lammertsma AA, Lubberink M: Quantitative parametric perfusion images using 15O-labeled water and a clinical PET/CT scanner: test-retest variability in lung cancer. J Nucl Med 2010, 51: 1684–1690. 10.2967/jnumed.110.079137
Article
PubMed
Google Scholar