Quantification of [11C]-meta-hydroxyephedrine uptake in human myocardium

EJNMMI Research

Table 1 Outcome parameters for various models

	All models	1T2k model	2T3k model	2T4k model
Outcome parameter	Unidirectional influx rate	Total volume of distribution	Total rate of irreversible binding	Total volume of distribution	Non-displaceable binding potential	Specific volume of distribution
Symbol	K ₁	V _T,1t	K _i	V _T,2t	BP_ND	V _S
Definition	-	$\frac{K_{1}}{k_{2}}$	$K_{1} • \frac{k_{3}}{k_{2} + k_{3}}$	$\frac{K_{1}}{k_{2}} • (1 + \frac{k_{3}}{k_{4}})$	$\frac{k_{3}}{k_{4}}$	$\frac{K_{1}}{k_{2}} • \frac{k_{3}}{k_{4}}$