Validation of dynamic [18F]FE-PE2I PET for estimation of relative regional cerebral blood flow: a comparison with [15O]H2O PET

EJNMMI Research

Table 2 rCBF_R measured with F and R1 in patients and healthy controls

Region	rCBF_R	Group	N	Mean	SD	SEM
Frontal cortex	F	Patients	29	0.37	0.03	0.005
	F	HC	30	0.38	0.03	0.005
	R1	Patients	29	0.93	0.04	0.008
	R1	HC	30	0.93	0.04	0.008
Parietal cortex	F	Patients	29	0.35	0.02	0.005
	F	HC	30	0.37	0.03	0.005
	R1	Patients	29	0.89	0.04	0.008
	R1	HC	30	0.92	0.04	0.008
Temporal cortex	F	Patients	29	0.36	0.03	0.005
	F	HC	30	0.38	0.03	0.006
	R1	Patients	29	0.86	0.05	0.009
	R1	HC	30	0.87	0.05	0.009
Cingulate cortex	F	Patients	29	0.44	0.04	0.008
	F	HC	30	0.44	0.04	0.008
	R1	Patients	29	0.95	0.05	0.009
	R1	HC	30	0.94	0.05	0.010
Occipital cortex	F	Patients	29	0.37	0.02	0.005
	F	HC	30	0.39	0.02	0.004
	R1	Patients	29	0.92	0.05	0.009
	R1	HC	30	0.94	0.05	0.009
Putamen	F	Patients	29	0.48	0.04	0.008
	F	HC	30	0.50	0.04	0.008
	R1	Patients	29	1.02	0.06	0.011
	R1	HC	30	1.07	0.06	0.012
Caudate	F	Patients	29	0.24	0.03	0.006
	F	HC	30	0.25	0.04	0.007
	R1	Patients	29	0.73	0.06	0.012
	R1	HC	30	0.76	0.08	0.014

Values are averaged over the left and right hemisphere. rCBF_R Relative regional cerebral blood flow, HC Healthy controls, rCBF_R relative regional cerebral blood flow, F rCBF_R measured with [¹⁵O]H₂O PET, R1 rCBF_R measured with [¹⁸F]FE-PE2I