EJNMMI Research

Table 1 Body/heart weights and glycemia measurements in vehicle and doxorubicin-treated rats

From: [¹²³I]MIBG is a better early marker of anthracycline cardiotoxicity than [¹⁸F]FDG: a preclinical SPECT/CT and simultaneous PET/MR study

	Control	Doxorubicin	p value
Body weight (g)
Baseline	222 ± 5	222 ± 4	ns
Week 2	274 ± 6	232 ± 3	p < 0.01
Week 4	305 ± 9	208 ± 3	p < 0.001
Week 6	322 ± 10	225 ± 14	p < 0.001
Left ventricle mass (mg)
Baseline	427 ± 22	423 ± 17	ns
Week 2	509 ± 20	413 ± 22	p < 0.01
Week 4	492 ± 20	384 ± 9	p < 0.01
Week 6	545 ± 21	446 ± 19	p < 0.01
Glycemia (mM)
Baseline	7.6 ± 0.3	6.9 ± 0.3	ns
Week 2	6.6 ± 0.2	6.9 ± 0.3	ns
Week 4	6.7 ± 0.2	6.7 ± 0.1	ns
Week 6	6.6 ± 0.2	6.0 ± 0.6	ns

ns not significant. Results are expressed as mean ± SEM

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