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Fig. 3 | EJNMMI Research

Fig. 3

From: A near-infrared probe for non-invasively monitoring cerebrospinal fluid flow by 18F-positron emitting tomography and fluorescence

Fig. 3

Non-radioactive IR783-AMBF3 can be visualized through deep tissue in the fluorescence mode. a Bright field images of rats (n = 2) with LP shunts that run superficially, under the skin of a shaved rat. b In vivo fluorescent images of the shunt in a rat after filling the shunt with IR783-AMBF3 (10 μM). c (Control) Comparative in vivo fluorescent imaging of a shunt filled with Fc-AMBF3 placed in a rat (1 mM, L5-L6). IR783-AMBF3 fluorescence is visible in the shunt, spine, and brain, and through skin, bone, and a viable shunt

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