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Table 2 Average SUVmean values obtained at 60 min post-injection of [18F]FSPG and [18F]FDG for each of the cancer types

From: Initial evaluation of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate (FSPG) PET/CT imaging in patients with head and neck cancer, colorectal cancer, or non-Hodgkin lymphoma

 

Head and neck cancer

Colorectal cancer

Non-Hodgkin lymphoma

SUV 60 min p.i. (g/ml)

[18F]FSPG

[18F]FDG

Ratio SUVFSPG/SUVFDG

[18F]FSPG

[18F]FDG

Ratio SUVFSPG/SUVFDG

[18F]FSPG

[18F]FDG

Ratio SUVFSPG/SUVFDG

 

(mean ± SD)

 

(mean ± SD)

 

(mean ± SD)

 

Primary

2.8 ± 2.1

4.9 ± 2.2

0.57

5.4 ± 1.3

6.9 ± 0.8

0.78

1.9 ± 3.1

1.9 ± 1.6

1.00

Metastases

1.3 ± 0.7

3.0 ± 1.4

0.43

2.5 ± 2.4

3.5 ± 3.5

0.71

-

-

 

Aorta

0.8 ± 0.3

1.6 ± 0.3

0.50

0.9 ± 0.4

1.9 ± 0.5

0.47

1.0 ± 0.3

1.7 ± 0.3

0.59

Pancreas

7.4 ± 1.4

1.7 ± 0.2

4.35

7.0 ± 1.4

1.7 ± 0.4

4.12

7.1 ± 1.7

1.9 ± 0.3

3.74

Heart

0.7 ± 0.1

2.4 ± 1.3

0.29

0.8 ± 0.4

3.9 ± 1.5

0.21

0.9 ± 0.1

2.0 ± 0.5

0.45

Kidney whole

9.8 ± 1.3

3.2 ± 0.6

3.06

16.1 ± 7.3

4.7 ± 2.6

3.43

11.4 ± 2.7

4.4 ± 1.4

2.59

Kidney cortex

8.2 ± 0.6

2.6 ± 0.1

3.15

11.3 ± 3.7

2.8 ± 1.0

4.04

10.6 ± 2.8

2.7 ± 0.4

3.93

Brain

0.1 ± 0.0

7.9 ± 1.4

0.01

0.12 ± 0.04

7.8 ± 2.0

0.01

0.1 ± 0.0

8.2 ± 3.6

0.01

Muscle

0.2 ± 0.04

0.7 ± 0.1

0.29

0.2 ± 0.1

0.6 ± 0.1

0.33

0.3 ± 0.1

0.8 ± 0.1

0.38

Lung

0.2 ± 0.04

0.4 ± 0.1

0.50

0.3 ± 0.1

0.5 ± 0.2

0.60

0.3 ± 0.1

0.5 ± 0.2

0.60

Liver

1.2 ± 0.3

2.3 ± 0.2

0.52

1.5 ± 0.4

2.3 ± 0.3

0.65

1.5 ± 0.1

2.6 ± 0.3

0.58

Tumor: brain

27.6

0.6

46.00

45.3

0.9

50.33

18.9

0.2

94.50

Tumor: aorta

3.3

3.0

1.10

5.7

3.7

1.54

1.9

1.1

1.73

Tumor: muscle

12.6

7.2

1.75

20.9

11.2

1.87

6.7

2.5

2.68

Tumor: liver

2.3

2.2

1.05

3.7

3.0

1.23

1.3

0.8

1.63

Tumor: pancreas

0.4

2.9

0.14

0.8

1.7

0.47

0.3

1

0.30

Tumor: kidney

0.3

1.5

0.20

3.4

1.5

2.27

0.2

0.4

0.50

  1. The tumor-to-background ratios are also shown and were taken with respect to six different relevant backgrounds: brain, aorta (blood pool), muscle (left gluteal muscle), liver, pancreas, and kidney