Skip to main content
EJNMMI Research

Table 2 Mean and standard deviations of binding parameter estimates obtained from 3 rats of the multi-injection study and from 4 rats of the partial saturation study

From: In vivo absolute quantification of striatal and extrastriatal D2/3 receptors with [123I]epidepride SPECT

Multi-injection study

Partial saturation

VOI

Bavail

± SD

appKD

±SD

Κ1

±SD

k2

±SD

kon

±SD

koff

±SD

Bavail

±SD

appKD

±SD

NAc

10.18

1.72

0.15

0.04

0.53

0.14

0.10

0.02

0.26

0.06

0.04

0.00

11.75

2.84

0.27

0.22

CP

24.22

2.62

0.22

0.06

0.69

0.16

0.10

0.04

0.21

0.06

0.04

0.01

21.25

1.25

0.08

0.03

VTA

3.77

1.86

0.34

0.21

0.57

0.07

0.14

0.04

0.28

0.36

0.04

0.02

4.01

1.40

–

–

FC

20.67

22.60

4.50

5.25

0.40

0.15

0.09

0.03

0.01

0.01

0.03

0.01

5.15

2.05

–

–

Amy

2.71

1.53

0.36

0.12

0.38

0.11

0.16

0.10

0.09

0.02

0.03

0.00

2.77

0.72

–

–

Hyp

3.64

1.10

0.37

0.09

0.50

0.21

0.13

0.03

0.15

0.03

0.05

0.01

3.85

0.90

–

–

SupC

3.86

1.65

0.28

0.18

0.70

0.19

0.16

0.04

0.26

0.20

0.05

0.02

3.97

0.93

–

–

InfC

3.03

0.40

0.18

0.02

0.80

0.26

0.17

0.03

0.23

0.02

0.04

0.00

4.46

0.45

–

–

Cer

2.02

1.09

0.65

0.27

0.66

0.18

0.20

0.02

0.04

0.03

0.02

0.01

–

–

–

–

  1. Bavail and appKd are in pmol/ml, K1 in mL.cm-3 .min-1, k2, k3, koff, in min-1
  2. NAc nucleus accumbens, CP caudate-putamen, VTA ventral tegmental area, FC frontal cortex, Amy amygdala, Hyp hypothalamus, SupC superior colliculus, InfC inferior colliculus, Cer cerebellum
Back to article page