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Correction to: In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography

Correction to: EJNMMI Res (2019) 9:87

https://doi.org/10.1186/s13550-019-0541-6

Following publication of the original article [1], the authors have reported an error in the ‘Histopathology’ (under ‘Materials and methods’) section of the article that compromises the reproducibility of the paper.

Namely, they have advised that the procedure for α5 integrin immunohistochemistry has not been reported correctly.

Unlike described in the paper, α5 IHC has been performed as follows:

“For alpha 5 integrin immunohistochemistry, a rabbit polyclonal antibody (LSBio, LS-B6179, diluted 1:7.500) was used. Immunohistochemistry was performed on a Leica BondRXm system (Leica, Wetzlar, Germany) using deparaffinization solution, pretreated with Epitope retrieval solution 2 (corresponding to EDTA buffer pH8) for 30 minutes. Antibody binding was detected with a polymer refine detection kit without post primary reagent and visualized with DAB as a dark brown precipitate.”

The authors apologize for this error.

Reference

  1. 1.

    Notni J, et al. In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography. EJNMMI Res. 2019;9:87. https://doi.org/10.1186/s13550-019-0541-6.

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Correspondence to Johannes Notni.

Additional information

The original article can be found online at https://doi.org/10.1186/s13550-019-0541-6

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Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Notni, J., Gassert, F.T., Steiger, K. et al. Correction to: In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography. EJNMMI Res 9, 107 (2019). https://doi.org/10.1186/s13550-019-0582-x

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