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Table 1 Plasma parameters in mice fed control or methionine- and choline-deficient (MCD) diet for 1 and 2 weeks

From: [18F]-BMS-747158-02PET imaging for evaluating hepatic mitochondrial complex 1dysfunction in a mouse model of non-alcoholic fatty liver disease

Parameter Control MCD 1 week MCD 2 weeks
TC (mg/dL) 91.1 ± 2.60 66.5** ± 3.85 52.3** ± 2.23
TG (mg/dL) 99.9 ± 15.6 31.6** ± 2.67 7.43** ± 1.71
AST (IU/L) 59.4 ± 18.6 367** ± 45.9 393** ± 108
ALT (IU/L) 25.1 ± 7.16 405** ± 67.1 256** ± 83.0
HDLC (mg/dL) 50.6 ± 1.61 36.1** ± 3.59 27.9** ± 2.08
  1. Data are expressed as the mean ± SEM of six mice per group. Statistical differences were assessed using Dunnett’s test
  2. TC total cholesterol, TG triglyceride, AST aspartate transaminase, ALT alanine aminotransferase, HDLC high-density lipoprotein cholesterol
  3. **p < 0.01 compared with the control mice