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EJNMMI Research

Table 4 Organ residence times of 18F-TFB in healthy participants

From: Safety, pharmacokinetics, metabolism and radiation dosimetry of 18F-tetrafluoroborate (18F-TFB) in healthy human subjects

Organ

Residence time males (min)

Residence time females (min)

Bone

4.6 ± 1.3

3.1 ± 0.3

Brain

1.2 ± 0.4

1.3 ± 0.2

Breast

–

2.8 ± 0.9

Gallbladder

0.06 ± 0.03

0.09 ± 0.04

Intestine

5.7 ± 1.9

13 ± 7

Kidney

4.2 ± 1.2

3.9 ± 0.8

Liver

8.3 ± 3.9

10 ± 2

Lung

2.1 ± 0.7

2.4 ± 0.2

Muscle

36 ± 14

26 ± 8

Myocardium

2.1 ± 0.6

1.8 ± 0.3

Pancreas

0.7 ± 0.3

0.58 ± 0.08

Parotid

1.7 ± 1.1

3.3 ± 1.2

Spleen

1.5 ± 0.4

1.6 ± 0.2

Stomach

11 ± 5

24 ± 12

Thyroid

2.0 ± 0.7

2.3 ± 0.9

Bladder

17 ± 2

19 ± 4

  1. Values are mean ± SD (n = 4)
  2. No significant (p < 0.05) differences were observed in organ residence times between genders
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