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EJNMMI Research

Table 2 Hepatic Ki and V(0) determined by previous workers [1,2,3] using computer modelling and Patlak-Rutland graphical analysis

From: The extent to which standardized uptake values reflect FDG phosphorylation in the liver and spleen as functions of time after injection of 18F-fluorodeoxyglucose

 

Modelling

Graphical analysis

Ki

V(0)

Ki/V(0)

Ki

V(0)

Ki/V(0)

Choi et al. [1]

0.0043

0.88a

0.0049

ND

ND

ND

Iozzo et al. [2]

0.0029

0.81

0.0036

0.0023

0.84b

0.0029b

Munk et al. [3]c

0.0078

0.95

0.0082

0.0037

1.05

0.0035

  1. Ki and V(0) based on modelling have been calculated using the equations linking Ki and V(0) to the transport constants (e.g. Ki = K 1 × k 3/[k 2 + k 3] and V(0) = K 1/[k 2 + k 3])
  2. Ki, ml/min/ml; V(0), ml/ml. Note that our mean value of Ki/V(0) was 0.0036 ml/min/ml
  3. ND not done
  4. FA – fat-adjusted
  5. aml/g
  6. bValues from single illustrated Patlak-Rutland plot (mean of group values not given)
  7. cAnaesthetized pigs
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