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Table 2 Hepatic Ki and V(0) determined by previous workers [1,2,3] using computer modelling and Patlak-Rutland graphical analysis

From: The extent to which standardized uptake values reflect FDG phosphorylation in the liver and spleen as functions of time after injection of 18F-fluorodeoxyglucose

  Modelling Graphical analysis
Ki V(0) Ki/V(0) Ki V(0) Ki/V(0)
Choi et al. [1] 0.0043 0.88a 0.0049 ND ND ND
Iozzo et al. [2] 0.0029 0.81 0.0036 0.0023 0.84b 0.0029b
Munk et al. [3]c 0.0078 0.95 0.0082 0.0037 1.05 0.0035
  1. Ki and V(0) based on modelling have been calculated using the equations linking Ki and V(0) to the transport constants (e.g. Ki = K 1 × k 3/[k 2 + k 3] and V(0) = K 1/[k 2 + k 3])
  2. Ki, ml/min/ml; V(0), ml/ml. Note that our mean value of Ki/V(0) was 0.0036 ml/min/ml
  3. ND not done
  4. FA – fat-adjusted
  5. aml/g
  6. bValues from single illustrated Patlak-Rutland plot (mean of group values not given)
  7. cAnaesthetized pigs