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EJNMMI Research
Fig. 4 | EJNMMI Research

Fig. 4

From: The extent to which standardized uptake values reflect FDG phosphorylation in the liver and spleen as functions of time after injection of 18F-fluorodeoxyglucose

Fig. 4

Time courses of total tissue activity estimated using Eq. 9 for slow exponential half-times of 40 min (left panel) and 60 min (right panel). V0 has been set to unity. The vertical axis is the total tissue activity (FDG6P + FDG) normalized to 100. When t is infinity, C t  = 0 and A t  = N/β (Eqs. 5 and 6). Therefore, when Ki/V(0) = β, the total activity is constant over post-injection time. For a slow exponential half-time of 40 min, β = 0.0173 min−1. Therefore, for values of Ki/V(0) > 0.0173 ml/min/ml, total activity increases as a function of post-injection time, and vice versa when Ki/V(0) < 0.0173 ml/min/ml. The boundary Ki/V(0) value for a slow exponential half-time of 60 min is 0.0115 ml/min/ml. Ignoring the small areas under the fast exponentials does not alter these time courses

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