Relationship between absorbed doses D and tumor metabolic ratio ( MR ). MR for the responding tumors are lower than 1. Each color refers to each patient (black - 1, blue - 2, brown - 3, red - 4, pink - 5, green - 6, cyan - 7, and grey - 8). Open circles and hexagons correspond to metastases from CRC, and open squares refer to metastases from melanoma. The patient gender and the Hb level (in gram per deciliter) on the day of the SIRT procedure are indicated at the extremity of each fitted line. Individual patient tumors were fitted by , where gf is the growing fraction in the absence of an absorbed dose and is the overall cell radiosensitivity, i.e., containing the HEF factor. The box in the upper left corner identifies outliers (see ‘Results and discussion’). The lines are the patient data individually fitted with this single exponential.