Table 1 Kinetic Parameter Values

K₁(mL.cm^-3.min^-1)

0.404 ± 0.087

0.44 ± 0.180

0.5

± 0.065

0.498 ± 0.097

0.480 ± 0.083

0.505 ± 0.071

0.570 ± 0.082

0.629 ± 0.065

k₂(min^-1)

0.076 ± 0.023

0.059 ± 0.034

0.069 ± 0.018

0.078 ± 0.021

0.094 ± 0.02

0.082 ± 0.018

0.102 ± 0.021

0.112 ± 0.027

k₃(min^-1)

0.032 ± 0.008

0.023 ± 0.014

0.036 ± 0.011

0.012 ± 0.006

0.019 ± 0.008

0.022 ± 0.011

0.021 ± 0.008

0.044 ± 0.043

k₄(min^-1)

0.018 ± 0.002

0.014 ± 0.003

0.018 ± 0.0009

0.024 ± 0.003

0.019 ± 0.005

0.023 ± 0.019

0.021 ± 0.009

0.042 ± 0.028

V_T(cortex) V_T‘(cerebellum)

(mL.cm^-3)

17.126

± 0.300

* †

19.905

± 1.607

* †

21.737

± 3.181

* †

11.467 ± 0.268

10.761 ± 3.098

12.941 ± 3.110

12.071 ± 3.033

11.328 ± 1.941

V_s= “K₁.k₃” /“k₂.k₄” (mL.cm^-3)

11.661 ± 1.010

* †

12.118 ± 2.513

* †

14.360 ± 3.297

* †

5.038 ± 0.757

5.481 ± 2.405

6.508 ± 2.078

6.332 ± 2.402

5.403 ± 0.965

\({V}_{b }\left(\frac{mL}{mL}\right)\)

0.040 ± 0.016

0.049 ± 0.037

0.052 ± 0.017

0.052 ± 0.017

0.042 ± 0.014

0.044 ± 0.011

0.056 ± 0.012

0.057 ± 0.018

Delay (s)

6.333 ± 1.528

6 ± 1

6.667 ± 1.528

7 ± 1

5.417 ± 1.730

5.417 ± 1.621

5.417 ± 1.929

6.083 ± 1.165