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Table 2 Adverse events

From: In-vivo inhibition of neutral endopeptidase 1 results in higher absorbed tumor doses of [177Lu]Lu-PP-F11N in humans: the lumed phase 0b study

Patient no

Definition

Grade w/o

Grade w

Patient no

Definition

Grade w/o

Grade w

1

Hot flashes

1

1

6

Hypocalcemia

1

1

Flush

1

1

6

Hypokalemia

1

1

Nausea

1

1

6

Headache

1

1

Dizziness

1

1

6

Hot flashes

1

1

Sweating

1

6

Nausea

1

1

1

Hypocalcemia

2

6

Flushing

1

1

2

Hypocalcemia

1

6

Hyperhidrosis

1

2

Dizziness

1

1

7

Flushing

1

1

2

Hyperhidrosis

1

1

7

Nausea

1

1

3

Abdominal pain

1

7

Vomiting

1

3

Paresthesia

1

7

Hyperhidrosis

1

3

Hot flashes

1

7

Hypokalemia

1

3

Dizziness

1

1

7

Fatigue

1

3

Nausea

1

1

8

Nausea

1

1

4

Hot flashes

1

1

8

Headache

1

1

4

Neck pain

1

1

8

Dizziness

1

5

Paresthesia

1

    
  1. Adverse effects without (w/o) and with (w) Entresto® premedication, graded according to CTCAE version 4.03