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Table 2 SPM group analysis

From: Brain 18 F-FDG PET reveals cortico-subcortical hypermetabolic dysfunction in juvenile neuropsychiatric systemic lupus erythematosus

SPM statistical thresholds*

p < 0.001 uncorrected

p < 0.05 FWE corrected

PET group vs. controls

All PET exams (n = 19)

All PET exams (n = 19)

First PET exams

(n = 11)

PET with minor NP scores (n = 11)

PET with major NP scores (n = 8)

Mean

Z-score

Mean

volume

Mean

Z-score

Mean

volume

Mean

Z-score

Mean volume

Mean

Z-score

Mean

volume

Mean

Z-score

Mean

volume

Whole brain

 

4,24

150,248

6,20

15,232

5,94

600

6,11

7744

5,85

4832

Cortex & hippocampus

Occipital**

4,06

25,888

5,77

1144

0

0

5,89

1720

0

0

Hippocampus & amygdala

3,93

6112

6

144

0

0

6

120

0

0

Frontal lobe

3,88

8384

0

0

0

0

5,69

432

0

0

Subcortical areas

Striatum & putamen

4,17

8328

5,75

192

0

0

0

0

5,72

192

Thalamus

5,40

11,064

6,56

5536

5,94

600

6,30

3752

5,83

1952

Sub-thalamic brainstem

4,85

7064

6,37

2256

0

0

6,05

1256

5,99

672

Cerebellar cortex

4,24

29,736

5,98

2816

0

0

5,50

16

5,89

1272

Vermis

4,52

6632

5,56

1088

0

0

0

0

0

0

  1. *extent threshold set to 50 voxels
  2. **primary & associative visual cortex, SPM Statistical Parametric Mapping, PET Positron Emission Tomography, NP Neuropsychiatric
  3. Minor NP score = all scores  1 (n = 11), Major NP scores = at least one score  2 (n = 8)