Fig. 5

Ex vivo brain autoradiography imaging using [¹¹C]SMW139 in APP/PS1-21 transgenic (TG) and wild type (WT) mice. a Representative autoradiography images of TG (n = 1) and WT (n = 1) mice at 8–10 months. Images are adjusted to the same color bar. b and c [¹¹C]SMW139 standardized uptake value (SUV) in cortex (b) and thalamus (c) of TG (n = 4, 5, 2, 2) and WT (n = 4, 7, 1, 5) mice at 5, 8–10, 12 and 14 months