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Fig. 4 | EJNMMI Research

Fig. 4

From: Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA

Fig. 4

[11C]SMW139 and [18F]F-DPA standardized uptake value (SUV) in the same APP/PS1-21 transgenic (TG) and wild type (WT) mice at 14 months. a and c [11C]SMW139 averaged SUV in the neocortex (a) and hippocampus (c) of TG (n = 3) and WT (n = 4) mice. b and d [18F]F-DPA averaged SUV in the neocortex (b) and hippocampus (d) of the same TG and WT mice. Statistical test: t-test with Welch’s correction. SUV values are presented with mean and standard deviation. *p < 0.05

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