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EJNMMI Research
Fig. 2 | EJNMMI Research

Fig. 2

From: Glial reactivity in a mouse model of beta-amyloid deposition assessed by PET imaging of P2X7 receptor and TSPO using [11C]SMW139 and [18F]F-DPA

Fig. 2

[11C]SMW139 longitudinal brain uptake in APP/PS1-21 transgenic (TG) and wild type (WT) mice. a and b Longitudinal [11C]SMW139 standardized uptake values (SUVs) in the neocortex and hippocampus of TG and WT mice at 5, 8, 11 and 14 months of age. Statistical analysis: linear mixed model with compound symmetry covariance structure. c Representative axial brain PET/CT images of [11C]SMW139 longitudinal SUVs in the same TG and WT mice at 5, 8, 11 and 14 months of age

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