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Table 1 Characteristics of enrolled patients according to MACE

From: Spherization indices measured by resting SPECT improve risk stratification in patients with ischemia with non-obstructive coronary artery disease (INOCA)

 

Total (N = 285)

MACE (N = 49)

Non-MACE (N = 236)

P value

Age (years)

56.6 ± 12.3

61.2 ± 11.5

55.7 ± 12.2

0.004

Women, n(%)

129 (45.3)

24 (49.0)

105 (44.5)

0.566

BMI (kg/m2)

24.7 ± 3.6

23.9 ± 3.4

24.8 ± 3.6

0.096

Clinical status

 Typical angina, n(%)

144 (50.5)

26 (53.1)

118 (50.0)

0.821

 Atypical angina, n(%)

98 (34.4)

17 (34.7)

81 (34.3)

 Non-anginal chest pain, n(%)

43 (15.1)

6 (12.2)

37 (15.7)

 Abnormal electrocardiogram, n(%)

170 (59.6)

27 (55.1)

143 (60.6)

0.476

Coronary artery stenosis

 Without detectable stenosis, n(%)

166 (58.2)

21 (42.9)

145 (61.4)

0.055

 1% ~ 24%, n(%)

74 (26.0)

17 (34.7)

57 (24.2)

 25% ~ 49%, n(%)

45 (15.8)

11 (22.4)

34 (14.4)

Medical history

 Hypertension, n(%)

128 (44.9)

26 (53.1)

102 (43.2)

0.208

 Diabetes, n(%)

38 (13.3)

10 (20.4)

28 (11.9)

0.109

 Smoking, n(%)

103 (36.1)

17 (34.7)

86 (36.4)

0.817

 Dyslipidemia, n(%)

17 (6.0)

4 (8.2)

13 (5.5)

0.475

 Cardiovascular family history, n(%)

92 (32.3)

20 (40.8)

72 (30.5)

0.160

Medications

 Anticoagulant/Antiplatelet, n(%)

219 (76.8)

41 (83.7)

178 (75.4)

0.213

 ACEI/ARB, n(%)

113 (39.6)

20 (40.8)

93 (39.4)

0.854

 Beta-blocker, n(%)

123 (43.2)

19 (38.8)

104 (44.1)

0.496

 CCB, n(%)

83 (29.1)

20 (40.8)

63 (26.7)

0.048

 Statin, n(%)

212 (74.4)

41 (83.7)

171 (72.5)

0.102

Laboratory variables

 Hemoglobin (g/L)

142.4 ± 15.0

137.0 ± 16.0

143.5 ± 14.6

0.006

 Red blood cell (× 1012/L)

4.6 ± 0.9

4.4 ± 0.5

4.7 ± 0.9

0.019

  1. ACEI, angiotensin converting enzyme inhibitors; ARB, angiotensin receptor blockers