EJNMMI Research

Table 3 Group differences in ¹⁸F-FDG PET SUVR relative to the pons

From: Comparison of ¹⁸F-FDG PET and arterial spin labeling MRI in evaluating Alzheimer’s disease and amnestic mild cognitive impairment using integrated PET/MR

Parameter	¹⁸F-FDG SUVR			P value
Parameter	NC	aMCI	AD	NC vs. aMCI	NC vs. AD	aMCI vs. AD
Orbitofrontal cortex	0.61 (0.06)	0.60 (0.09)	0.57 (0.07)	0.595	0.005	0.064
Prefrontal cortex	0.68 (0.06)	0.65 (0.10)	0.62 (0.08)	0.108	< 0.001	0.039
Superior frontal cortex	0.73 (0.06)	0.71 (0.09)	0.63 (0.10)	0.323	< 0.001	< 0.001
Lateral temporal	0.63 (0.05)	0.59 (0.07)	0.53 (0.07)	0.001	< 0.001	0.001
Medial temporal	0.50 (0.04)	0.47 (0.07)	0.46 (0.05)	0.001	< 0.001	0.917
Inferior temporal	0.61 (0.05)	0.58 (0.05)	0.53 (0.07)	0.003	< 0.001	< 0.001
Parietal	0.67 (0.06)	0.65 (0.10)	0.51 (0.10)	0.155	< 0.001	< 0.001
Posterior precuneus	0.82 (0.07)	0.81 (0.11)	0.62 (0.13)	0.413	< 0.001	< 0.001
Posterior cingulate	0.84 (0.07)	0.82 (0.12)	0.63 (0.11)	0.358	< 0.001	< 0.001
Hippocampus	0.52 (0.04)	0.48 (0.06)	0.45 (0.06)	< 0.001	< 0.001	0.039
Parahippocampus	0.52 (0.05)	0.48 (0.06)	0.46 (0.05)	0.001	< 0.001	0.081

Data were presented with mean (standard deviation). There was a significantly decreased ¹⁸F-FDG PET SUVR in AD compared to NC in all 11 ROIs, AD compared to aMCI in 8 ROIs, and aMCI compared to NC in 5 ROIs. P < 0.05 indicate statistical significance

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