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EJNMMI Research

Table 4 Kinetic parameters estimates from 14 ROIs, gray and white matter and whole brain

From: A short 18F-FDG imaging window triple injection neuroimaging protocol for parametric mapping in PET

 

2TCM (24 min short window)

Patlak (validation window) \(K_{i}\)(ml/g/min)

Relative error (%) in \(K_{i}\) (short window against validation window)

Region

\(K_{1}\)(ml/g/min)

\(k_{2}\)(1/min)

\(k_{3}\)(1/min)

\(K_{i}\)(ml/g/min)

Caudate

0.07 ± 0.02

0.11 ± 0.04

0.04 ± 0.02

0.020 ± 0.007

0.020 ± 0.006

0.5 ± 3.8

Cerebellum

0.10 ± 0.04

0.16 ± 0.07

0.04 ± 0.02

0.018 ± 0.007

0.017 ± 0.005

3.3 ± 8.5

Cingulum Ant

0.08 ± 0.03

0.12 ± 0.04

0.05 ± 0.02

0.025 ± 0.008

0.023 ± 0.006

7.2 ± 4.2

Cingulum Post

0.08 ± 0.03

0.12 ± 0.05

0.05 ± 0.02

0.021 ± 0.009

0.021 ± 0.008

1.3 ± 2.4

Hippocampus

0.08 ± 0.02

0.12 ± 0.04

0.04 ± 0.02

0.018 ± 0.007

0.018 ± 0.005

− 0.2 ± 5.3

Insula

0.08 ± 0.02

0.12 ± 0.04

0.05 ± 0.02

0.024 ± 0.007

0.022 ± 0.005

6.9 ± 3.6

Putamen

0.08 ± 0.02

0.12 ± 0.04

0.05 ± 0.01

0.023 ± 0.007

0.022 ± 0.005

8.0 ± 4.6

Occipital

0.08 ± 0.03

0.12 ± 0.04

0.05 ± 0.02

0.023 ± 0.008

0.023 ± 0.006

1.3 ± 4.1

Parietal

0.08 ± 0.02

0.1 ± 0.03

0.05 ± 0.02

0.024 ± 0.007

0.024 ± 0.006

2.0 ± 4.0

Lingual

0.09 ± 0.03

0.13 ± 0.05

0.05 ± 0.02

0.024 ± 0.007

0.023 ± 0.006

5.3 ± 3.3

Temporal Mid

0.08 ± 0.02

0.11 ± 0.04

0.05 ± 0.02

0.022 ± 0.008

0.022 ± 0.006

2.0 ± 3.6

Amygdala

0.08 ± 0.03

0.12 ± 0.06

0.04 ± 0.02

0.020 ± 0.008

0.020 ± 0.007

0.2 ± 4.5

Thalamus

0.08 ± 0.02

0.11 ± 0.04

0.05 ± 0.01

0.021 ± 0.006

0.020 ± 0.005

6.3 ± 4.2

White matter

0.05 ± 0.01

0.07 ± 0.02

0.03 ± 0.01

0.012 ± 0.004

0.014 ± 0.003

− 17.3 ± 15.4

Gray Matter

0.08 ± 0.03

0.11 ± 0.04

0.04 ± 0.02

0.021 ± 0.008

0.021 ± 0.006

2.0 ± 5.0

Whole Brain (mean)

0.08 ± 0.02

0.12 ± 0.04

0.04 ± 0.02

0.021 ± 0.007

0.021 ± 0.006

1.9 ± 5.1

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