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Table 2 Diagnostic performance of [18F]FDOPA and [68Ga]-DOTATOC PET in primary adrenal disease (patient- and lesion-based analysis)

From: [18F]FDOPA PET/CT is superior to [68Ga]DOTATOC PET/CT in diagnostic imaging of pheochromocytoma

 

[18F]FDOPA

[68Ga]DOTATOC

Patient-based (N = 97)

 Sensitivitya

51/51 (100%)

25/51 (49%)

 Specificity

38/40 (95%)

39/40 (98%)

 PPV

51/53 (96%)

25/26 (96%)

 NPVa

40/40 (100%)

39/65 (63%)

 Diagnostic accuracya

90/92 (98%)

64/91 (70%)

Lesion-based (N = 194)

 Sensitivitya

55/55 (100%)

27/55 (49%)

 Specificity

136/139 (98%)

138/139 (99%)

 PPV

55/58 (95%)

27/28 (96%)

 NPVa

136/136 (100%)

138/166 (83%)

 Diagnostic accuracya

191/194 (98%)

165/194 (85%)

  1. PPV positive predictive value, NPV negative predictive value
  2. aMean value of patients with PCC is significantly different compared with mean of patients without PCC (P < 0.001)