Fig. 2

Global proteomic analyses in H2030-BrM3 lung-derived brain metastasis (BM) vs healthy brain tissues. a Volcano plots of quantified proteins between BM vs healthy brain tissues. Significant differentially expressed proteins are shown in red, cut-off: fold change (FC) = log2(1.2) (FC = 2.3) and p < 0.01, Bonferroni test. b GO enrichments of differentially expressed proteins on biological processes (BP). **FDR 1%, *FDR 5%. n = 5 for BM and n = 3 for healthy brain tissues