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EJNMMI Research

Table 2 Univariate and multivariate analysis for recurrence-free survival

From: Evaluation of recurrence risk for patients with stage I invasive lung adenocarcinoma manifesting as solid nodules based on 18F-FDG PET/CT, imaging signs, and clinicopathological features

Variable

Univariable analysis

Multivariable analysis

HR

95% CI

P

HR

95% CI

P

Age (years)

0.997

0.968–1.028

0.861

   

Male

1.051

0.595–1.857

0.863

   

Smoking

      

Hypertension

1.468

0.831–2.593

0.186

   

Diabetes

1.237

0.555–2.758

0.603

   

IASLC grading

  

 < 0.001

  

 < 0.001

  Grade 1 (Ref.)

      

  Grade 2

1.556

0.547–4.427

0.407

1.265

0.393–4.077

0.694

  Grade 3

7.083

2.321–21.655

0.001

3.957

1.111–14.092

0.034

Tumor size

1.082

1.046–1.120

 < 0.001

   

T stage

2.221

1.589–3.102

 < 0.001

   

Lobulation

1.274

0.723–2.246

0.402

   

Spiculation

0.813

0.405–1.632

0.560

   

Cavity sign

4.912

2.087–11.563

 < 0.001

5.381

2.234–12.961

 < 0.001

Air bronchogram

0.609

0.189–1.961

0.406

   

Vessel convergence

0.424

0.058–3.072

0.395

   

Pleural indentation

1.173

0.663–2.075

0.584

   

SUVmax

1.247

1.163–1.336

 < 0.001

1.225

1.133–1.326

 < 0.001

SUVmean

1.412

1.266–1.574

 < 0.001

   

MTV

1.037

1.010–1.065

0.006

1.045

1.009–1.082

0.045

TLG

1.018

1.011–1.024

 < 0.001

   
  1. SUVmax maximum standard uptake value, SUVmean mean standard uptake value, MTV metabolic tumor volume, TLG total lesion glycolysis
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