Table 1 Summary of biodistribution, decay-corrected percentage injected activity (%IA) in blood, PK population (N = 8)
From: Safety, biodistribution and radiation dosimetry of [123I]ioflupane in healthy Chinese volunteers
Time after dosing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Tissue | Predose | 5 min | 15 min | 30 min | 1 h | 2 h | 3 h | 4 h | 5 h | 24 h | 48 h |
Plasma | |||||||||||
Mean (SD) | 0.016 (0.007) | 2.769 (0.773) | 1.686 (0.557) | 1.350 (0.293) | 1.351 (0.267) | 1.375 (0.340) | 1.338 (0.385) | 1.229 (0.336) | 1.138 (0.300) | 0.768 (0.181) | 0.626 (0.138) |
Whole blood | |||||||||||
Mean (SD) | 0.030 (0.009) | 4.564 (1.471) | 2.798 (0.941) | 2.220 (0.504) | 2.220 (0.472) | 2.355 (0.550) | 2.216 (0.550) | 2.081 (0.492) | 1.924 (0.403) | 1.348 (0.339) | 1.098 (0.344) |