Skip to main content
EJNMMI Research

Table 2 Regional [18F]FE-PE2I BPND values and corresponding effect sizes in PD versus HC

From: [18F]FE-PE2I DAT correlates with Parkinson’s disease duration, stage, and rigidity/bradykinesia scores: a PET radioligand validation study

Brain region

PD n = 41 (mean ± SD)

HC n = 37 (mean ± SD)

p value

Effect size

Asymmetry index (%)

PD (median; range)

HC (95% CI)

Striatum

1.61 ± 0.49

4.01 ± 0.69

 < 2.2e−16

1.79

24.7; 5.4–64.9

2.5–4.4

Caudate nucleus

1.81 ± 0.64

3.31 ± 0.68

8.7e−16

1.50

18.8; 0.7–87.1

4.5–7.9

Putamen*

1.36 ± 0.44

4.68 ± 0.80

 < 2.2e−16

1.86

30.9; 3.6–74.8

1.9–3.5

Ventral striatum (VS)

2.21 ± 0.54

2.93 ± 0.45

5.6e−09

1.18

7.1; -20.5–49.1

9.8–14.2

Sensorimotor striatum (SMS)*

0.87 ± 0.34

4.24 ± 0.89

 < 2.2e−16

1.85

32.4; -17.6–90.0

9.2–13.6

Substantia nigra (SN)

0.69 ± 0.14

1.01 ± 0.17

2.0e−14

1.45

16.6; -28.0–43.7

7.2–11.4

  1. *Non-equal variance between PD and HC groups. P value was calculated with a one-tailed, independent t test. PD subjects with Parkinson’s disease, HC healthy controls, CI confidence interval
Back to article page