The potential application of MR-derived ADCmin values from 68Ga-DOTATATE and 18F-FDG dual tracer PET/MR as replacements for FDG PET in assessment of grade and stage of pancreatic neuroendocrine tumors

EJNMMI Research

Table 3 Parameters of ⁶⁸Ga-DOTATATE and ¹⁸F-FDG dual tracer PET/MR based on N stage and M stage

Parameters	N0	N1	P (N0 v N1)	M0	M1	P (M0 v M1)
FSUVmax	2.7 (2.1–8.1)	5.9 (5.1–11.5)	0.07	2.6 (2.1–11.1)	5.3 (4.1–7.8)	0.17
MTV	2.6 (1.2–14.1)	25.3 (2.5–51.6)	0.07	2.5 (1.0–10.9)	22.1 (2.5–40.0)	0.03
TLG	4.5 (1.9–72.1)	96.8 (9.5–396.1)	0.03	4.3 (1.8–70.9)	60.3 (9.3–199.0)	0.03
GSUVmax	56.1 (24.5–85.1)	27.8 (16.1–95.1)	0.55	51.4 (25.3–89.5)	59.7 (14.3–83.0)	0.63
SRD	6.9 (3.1–20.5)	30.7 (17.3–70.4)	0.01	6.2 (3.0–22.7)	25.6 (11.1–91.9)	< 0.01
TLSRD	121.8 (59.1–328.6)	264.4 (118.7–849)	0.24	115.3 (59.7–318.6)	271.7 (103.3–2689.6)	0.17
ADCmin	840.4 ± 152.7	510.4 ± 216.5	< 0.01	843.0 ± 167.8	600.1 ± 201.8	< 0.01
ADCmean	1446.8 ± 283.1	1084.1 ± 199.6	< 0.01	1458.3 ± 282.0	1151.5 ± 246.2	< 0.01