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EJNMMI Research

Table 2 Error analysis results from Monte Carlo simulations for 90-min scan duration

From: Development of a minimally invasive simultaneous estimation method for quantifying translocator protein binding with [18F]FEPPA positron emission tomography

Brain region

True value

Simulated results (Mean ± SD)

VND (ml/cm3)

VT (ml/cm3)

VS (ml/cm3)

BPND

VND (ml/cm3)

VT (ml/cm3)

VS (ml/cm3)

BPND

Frontal

2.35

14.30

11.95

5.10

2.34

14.28 (T13.4–S15.1)

11.93 (T11.1–S12.7)

5.13 (T4.6–S5.6)

Temporal

15.16

12.81

5.45

15.14 (T14.6–S15.8)

12.80 (T12.3–S13.5)

5.51 (T5.0–S6.0)

Cerebellum

11.69

9.34

3.98

11.52 (T10.1–S11.8)

9.18 (T7.9–S9.7)

3.95 (T3.3–S4.4)

Thalamus

11.80

9.45

4.02

11.78 (T11.0–S12.1)

9.44 (T8.6–S9.6)

4.06 (T3.5–S4.4)

Insula

15.10

12.75

5.42

15.0 (T14.3–S15.6)

12.66 (T12.0–S13.1)

5.45 (T5.0–S5.9)

Caudate

13.80

11.45

4.87

13.80 (T12.8–S14.8)

11.46 (T10.5–S12.4)

4.88 (T4.7–S5.1)

  1. T25th percentile and S75th percentile
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