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Fig. 4 | EJNMMI Research

Fig. 4

From: Synthesis and preclinical evaluation of novel 99mTc-labeled PSMA ligands for radioguided surgery of prostate cancer

Fig. 4

Static µSPECT/CT images (maximum intensity projections) of 99mTc-labeled N4-PSMA-derivatives and [99mTc]Tc-PSMA-I&S in LNCaP tumor-bearing mice. Animals were sacrificed at 6 h p.i. and imaged directly after blood collection for 45 min on a VECTor4 small-animal SPECT/PET/OI/CT. Tracer uptake in tumor and kidneys (in percent of the injected dose/gram, (% ID/g)) was determined from subsequent biodistribution studies

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