Fig. 3
From: PARP targeted Auger emitter therapy with [125I]PARPi-01 for triple-negative breast cancer
A Scheme of the four cycles therapy with [125I]PARPi-01 in TNBC xenografted NOD/SCID mice. B Percentage tumour growth over time shows a delay upon treatment with [125I]PARPi-01. C Kaplan–Meier survival curve of mice during the therapeutic study with mice administered with either 0.9% Saline or [125I]PARPi-01 in 4 doses (10 days apart; control: n = 10; therapy: n = 10). Dashed lines show survival curve that excludes animals that were eliminated due to ulcer formation (control: n = 3; therapy: n = 5) D Percentage of Injected dose per gram tissue (%ID/g) over time for liver E. for tumour and F. for muscle