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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: First-in-human use of 11C-CPPC with positron emission tomography for imaging the macrophage colony-stimulating factor 1 receptor

Fig. 1

Plasma activity after injection of 11C-CPPC. (A) HPLC tracing at 60 min post-injection (p.i.) from a representative participant that demonstrates evidence of two radiolabeled metabolites in addition to the peak for parent 11C-CPPC. (B) Parent fraction (mean with standard deviation) measured at select time points (dots) over 90 min p.i., shown with linear interpolation. (C) Radioactivity curves in total plasma (solid line) and the portion of unmetabolized 11C-CPPC (dotted line) p.i. Inset shows early time points. Radioactivity is in standardized uptake value, SUV (injected dose per mL plasma normalized to body weight in grams)

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