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Fig. 4 | EJNMMI Research

Fig. 4

From: Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases

Fig. 4

Protein expression of TrkA and TrkB. A Original gel of selected samples from KM12 tumor tissue, brown adipose tissue (BAT), white adipose tissue (AT), and the whole brain from KM12 tumor-bearing mice, control wild type (WT), and TrkB 50% KO mice from combined red (700 nm) and green (800 nm) light wavelength analysis showing using antibodies for TrkA and TrkB and β-actin as housekeeping gene. For the full-length gel please, see Additional file 1: Fig. S5. B Semiquantitative comparison of TrkA and TrkB protein levels in brain samples from KM12 tumor-bearing mice, control wild type (WT), and TrkB 50% KO mice. C Semiquantitative comparison of TrkB protein levels in BAT and KM12 tumor tissue from KM12 tumor-bearing mice, control wild type (WT), and TrkB 50% KO mice. D Semiquantitative comparison of TrkB protein levels in white adipose tissue (AT) from KM12 tumor-bearing mice, control wild type (WT), and TrkB 50% KO mice. B–D All data are shown as normalized ratios (Trk / β-actin) and as mean ± SEM from 5 different tissue samples. * p < 0.05; n.s.—not significant

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