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EJNMMI Research
Fig. 5 | EJNMMI Research

Fig. 5

From: [18F]ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer’s disease pathology in APP/PS1 mice

Fig. 5

DHE colocalizes with microglia and neurons, but not astrocytes, in the APP/PS1 brain. Representative confocal micrographs showing colocalization of a, b oxidized DHE (red) with neurons (NeuN; green) and c, d microglia (IBA-1; green) in WT and APP/PS1 cortex. e, f Oxidized DHE did not colocalize with astrocytes (GFAP, green). The inlet is a magnified region of that indicated by the white arrow. Scale bar = 20 µm

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