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EJNMMI Research
Fig. 1 | EJNMMI Research

Fig. 1

From: Feasibility of fluorescence imaging at microdosing using a hybrid PSMA tracer during robot-assisted radical prostatectomy in a large animal model

Fig. 1

Excretion of EuK‐(SO3)Cy5‐mas3 in a porcine model. A Anatomical overview of vascular and urinary tract (with location of kidney, bladder, and prostate (basal PSMA expression) highlighted). Image was created using 3D-pig-anatomy software from Biosphera. Insert: Structure of EuK‐(SO3)Cy5‐mas3 [25] with the Euk targeting moiety highlighted in green, the bridging (SO3)Cy5 dye in gray and the mas3 chelate in pink. B Excretion of EuK‐(SO3)Cy5‐mas3 from the blood (in blue) and urine (in orange) was measured over time after intravenous tracer administration (T = 0–T = 420 min). C Fluorescence confocal microscopy images of fresh excised tissue specimens obtained after in vivo imaging (red on black; top images per organ) and antibody-based PSMA immunohistochemistry (IHC; bottom images per organ) of these tissues

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