Table 8 Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PSA > 20 ng/mL and ISUP > 3 for the detection of metastasis on [18F]PSMA-1007 PET/CT
From: Risk of metastatic disease using [18F]PSMA-1007 PET/CT for primary prostate cancer staging
Sensitivity | Specificity | Positive predictive value (PPV) | Negative predictive value (NPV) | Accuracy | |
|---|---|---|---|---|---|
PSA > 20 ng/mL | 36% (95% CI 25–49%) | 85% (95% CI 78–91%) | 56% (95% CI 40–71%) | 72% (95% CI 64–79%) | 69% (95% CI 62%–75%) |
ISUP > 3 | 62% (95% CI 49–74%) | 60% (95% CI 50–68%) | 43% (95% CI 33–54%) | 76% (95% CI 66–84%) | 60% (95% CI 53%–67%) |