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Table 8 Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PSA > 20 ng/mL and ISUP > 3 for the detection of metastasis on [18F]PSMA-1007 PET/CT

From: Risk of metastatic disease using [18F]PSMA-1007 PET/CT for primary prostate cancer staging

 

Sensitivity

Specificity

Positive predictive value (PPV)

Negative predictive value (NPV)

Accuracy

PSA > 20 ng/mL

36% (95% CI 25–49%)

85% (95% CI 78–91%)

56% (95% CI 40–71%)

72% (95% CI 64–79%)

69% (95% CI 62%–75%)

ISUP > 3

62% (95% CI 49–74%)

60% (95% CI 50–68%)

43% (95% CI 33–54%)

76% (95% CI 66–84%)

60% (95% CI 53%–67%)