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Table 8 Sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PSA > 20 ng/mL and ISUP > 3 for the detection of metastasis on [18F]PSMA-1007 PET/CT

From: Risk of metastatic disease using [18F]PSMA-1007 PET/CT for primary prostate cancer staging

  Sensitivity Specificity Positive predictive value (PPV) Negative predictive value (NPV) Accuracy
PSA > 20 ng/mL 36% (95% CI 25–49%) 85% (95% CI 78–91%) 56% (95% CI 40–71%) 72% (95% CI 64–79%) 69% (95% CI 62%–75%)
ISUP > 3 62% (95% CI 49–74%) 60% (95% CI 50–68%) 43% (95% CI 33–54%) 76% (95% CI 66–84%) 60% (95% CI 53%–67%)