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EJNMMI Research

Table 7 Proportion of metastases by EAU risk groups (intermediate-risk vs high-risk group based on PSA and ISUP grade) (n = 189) on [18F]PSMA-1007 PET/CT

From: Risk of metastatic disease using [18F]PSMA-1007 PET/CT for primary prostate cancer staging

 

Intermediate-risk (PSA 10–20 ng/mL or ISUP 2 and 3)

High-risk (PSA > 20 ng/mL or ISUP 4 and 5)

p-value

 

n = 71

n = 118

 

SUVmax of primary tumoura

11.9 (8.4–21.1)

20.2 (12.0–32.5)

< 0.001

Nodal metastasis(regional and non-regional)b

1.4% (1)

34.7% (41)

< 0.001

Bone metastasisb

8.5% (6)

28.0% (33)

0.001

Visceral metastasisc

2.8% (2)

4.2% (5)

0.71

  1. aMann-Whitney U test
  2. bChi-squared test
  3. cFisher’s exact test; n = 2 with missing ISUP grade information and PSA < 20 ng/mL (undetermined risk group) and n = 3 with PSA < 10 and ISUP = 1(low risk) were excluded; % (n) = percentage of patients (number of patients)
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