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Table 6 Inflamed to normal paw ratios of [68Ga]Ga-4HMSA and [68Ga]Ga-citrate from PET imaging and biodistribution results

From: [68Ga]Ga-4HMSA a promising new PET tracer for imaging inflammation

Time post-CFA administration

Inflamed/normal paw ratios from PET imaging

Inflamed to normal paw ratios from biodistribution

[68Ga]Ga-4HMSA

[68Ga]Ga-citrate

[68Ga]Ga-4HMSA

[68Ga]Ga-citrate

Day 1

2.73 ± 0.59

2.54 ± 0.67

2.13 ± 0.28

1.94 ± 0.35

Day 2

1.94 ± 0.18

2.03 ± 0.62

1.32 ± 0.06

1.71 ± 0.23

Day 3

1.56 ± 0.15

2.27 ± 0.61

1.19 ± 0.07

1.69 ± 0.23

Day 7

2.72 ± 0.65

2.79 ± 0.96

1.34 ± 0.68

1.67 ± 0.30