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Table 6 Inflamed to normal paw ratios of [68Ga]Ga-4HMSA and [68Ga]Ga-citrate from PET imaging and biodistribution results

From: [68Ga]Ga-4HMSA a promising new PET tracer for imaging inflammation

Time post-CFA administration Inflamed/normal paw ratios from PET imaging Inflamed to normal paw ratios from biodistribution
[68Ga]Ga-4HMSA [68Ga]Ga-citrate [68Ga]Ga-4HMSA [68Ga]Ga-citrate
Day 1 2.73 ± 0.59 2.54 ± 0.67 2.13 ± 0.28 1.94 ± 0.35
Day 2 1.94 ± 0.18 2.03 ± 0.62 1.32 ± 0.06 1.71 ± 0.23
Day 3 1.56 ± 0.15 2.27 ± 0.61 1.19 ± 0.07 1.69 ± 0.23
Day 7 2.72 ± 0.65 2.79 ± 0.96 1.34 ± 0.68 1.67 ± 0.30