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EJNMMI Research
Fig.4 | EJNMMI Research

Fig.4

From: Thrombocytopenia after meta-iodobenzylguanidine (MIBG) therapy in neuroblastoma patients may be caused by selective MIBG uptake via the serotonin transporter located on megakaryocytes

Fig.4

Relation between mature megakaryocytes and specific substrate uptake. The specific substrate uptake of serotonin (left y-axis) and MIBG (right y-axis) was plotted against the percentage of mature megakaryocytes (CD34−/CD41a+/CD42a+/CD42b+) in the culture batch. Data from megakaryocytic cell culture batches from three different healthy adult HSPC donors (MK1-3) are plotted (mean ± SD)

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