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Fig. 4 | EJNMMI Research

Fig. 4

From: Competitive blocking of salivary gland [18F]DCFPyL uptake via localized, retrograde ductal injection of non-radioactive DCFPyL: a preclinical study

Fig. 4

a Experiment design for intraglandular blocking study. b, c Tissue/blood ratios of [18F]DCFPyL in salivary glands (submandibular: SMG, sublingual: SLG, parotid: PRG, right: R, left: L; b and kidneys (c) at 1 h after injection. SMG glands were cannulated infused either with saline (CAN saline control) or with 25 µl or 50 µl of DCFPyL at 0.01, 0.1, 1 × molar excess of the systemically injected “hot” [18F]DCFPyL dose. Ten minutes after SMG infusion, mice were injected with [18F]DCFPyL. Each value in the graph represents mean tissue/blood ratios ± SD, n = 4–6 for each group

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