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Fig. 6 | EJNMMI Research

Fig. 6

From: Intraoperative visualization of nerves using a myelin protein-zero specific fluorescent tracer

Fig. 6

Translation of Cy5-P0101–125 into large animal models using clinical grade imaging modalities. A Surgical set-up showing the Da Vinci surgical robot and the use of a clinical grade STORZ fluorescence laparoscope dedicated for Cy5 imaging [42]. B Brightfield image of the pudendal nerve (white arrow). C In vivo fluorescence imaging of the pudendal nerve after intraneural administration of Cy5-P0101–125 as visible on the screen of the imaging set-up. Insert showing a colour-coded processed image of the fluorescence in the nerve. D Ex vivo fluorescence image of the excised nerve (left image) with corresponding colour-coded image-processing (right image) and scale bar depicting the corresponding nerve-to-background ratio (NBR)

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