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Table 1 Regional estimates of VT- and BPND for test-, and retest scans

From: The pharmacokinetics of [18F]UCB-H revisited in the healthy non-human primate brain

Brain region 2TCM 2TCM-c 1TCM Logan (t* = 60) 2TCM-c
VT [mL/cm3] VT [mL/cm3] VT [mL/cm3] VT [mL/cm3] k3/k4 (BPND)
Mean  ±  SEM Mean  ±  SEM Mean  ±  SEM Mean  ±  SEM Mean  ±  SEM
Striatum
Test 15.3  ±  2.25 15.0  ±  1.11 14.2  ±  1.29 15.8  ±  1.15 1.16  ±  0.36
Retest 14.1  ±  0.96 15.3  ±  0.93 14.8  ±  0.61 15.7  ±  1.04 1.12  ±  0.39
Thalamus
Test 15.6  ±  1.98 15.0  ±  1.38 13.3  ±  1.17 14.9  ±  0.99 1.03  ±  0.25
Retest 13.0  ±  1.08 14.2  ±  1.06 13.4  ±  0.60 14.3  ±  1.11 0.97  ±  0.36
Cerebellum
Test 10.6  ±  0.08 9.70  ±  NA 9.8  ±  0.78 11.2  ±  0.68 1.24  ±  NA
Retest 12.3  ±  NA 13.3  ±  2.97 10.4  ±  0.82 11.1  ±  0.75 1.22  ±  0.42
White matter
Test 14.0  ±  2.37 13.8  ±  1.69 12.3  ±  1.13 13.9  ±  1.00 1.25  ±  0.16
Retest 12.6  ±  1.08 13.7  ±  1.61 12.5  ±  0.68 13.6  ±  1.23 0.83  ±  0.47
Frontal cortex
Test 16.3  ±  3.68 14.8  ±  2.15 13.8  ±  1.64 15.0  ±  1.59 1.25  ±  0.32
Retest 13.1  ±  0.66 14.7  ±  1.37 13.8  ±  1.15 14.8  ±  1.87 1.32  ±  0.40
Temporal cortex
Test 13.9  ±  1.60 14.8  ±  1.30 12.9  ±  0.83 14.1  ±  0.77 1.00  ±  0.24
Retest 14.0  ±  0.01 13.1  ±  0.76 13.0  ±  0.52 13.9  ±  0.91 0.97  ±  0.54
Parietal cortex
Test 15.5  ±  3.24 15.4  ±  1.54 14.3  ±  1.41 15.4  ±  1.35 1.08  ±  0.26
Retest 13.6  ±  0.36 16.1  ±  1.40 14.8  ±  0.75 15.7  ±  1.43 1.17  ±  0.29
  1. VT was estimated using 2TCM, 2TCM-c, 1TCM and Logan. BPND was estimated by k3/k4 using a 2TCM-c. Only estimates at < 25%SE were included. NA = undetermined