Fig. 3
From: The pharmacokinetics of [18F]UCB-H revisited in the healthy non-human primate brain
a According to the lowest Akaike Information Criterion (AIC), the two-compartment model (2TCM, full line) fitted better the TACs (here striatum, circles) compared to the one-compartment model (1TCM, dashed line). b Logan graphical linear fit of striatal TAC (circles) with t* fixed at 60 min. c Dose dependent displacement of [18F]UCB-H at 90 min after radioligand injection by [19F]UCB-H at 80 µg/kg (red) and 5 mg/kg (blue). Slower brain penetrance of LEV (30 mg/kg, black) induced a slower displacement