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Table 1 Biodistribution of accumulated radioactivity (SUV) in various tissues at the designed time points after administration of [18F]FEPPA

From: GMP-compliant fully automated radiosynthesis of [18F]FEPPA for PET/MRI imaging of regional brain TSPO expression

Tissues Control LPS (5 mg/kg)
Blood 1.29 ± 0.03 1.29 ± 0.128
Heart muscle 1.24 ± 0.06 3.60 ± 0.722*
Liver 1.48 ± 0.36 1.60 ± 0.097
Lung 1.38 ± 0.08 3.60 ± 0.722**
Spleen 1.16 ± 0.32 0.96 ± 0.443
Kidney 4.80 ± 0.57 5.86 ± 0.504
Whole brain 0.48 ± 0.05 0.76 ± 0.014
  1. Data are mean ± SEM
  2. *p < 0.05; **p < 0.01, One-way ANOVA with Bonferroni post hoc test