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Table 2 Recruiting and not yet recruiting trials for FAP-specific PET for non-malignant indications on clinicaltrials.gov

From: Clinical results of fibroblast activation protein (FAP) specific PET for non-malignant indications: systematic review

Title

Estimated enrollment

Estimated Study completion Date

Indication

Tracer

Location

Key Interventions

Characterizing Rheumatoid Arthritis With 68Ga-FAPI PET/CT

100 patients

10/2021

Arthritis

Not specified

Peking Union Medical College Hospital

Patients who underwent FDG PET for suspected or confirmed untreated arthritis will receive and additional FAP-specific PET within two weeks

Characterizing Inflammatory Bowel Disease With 68Ga-FAPI PET/CT

100 patients

10/2021

Inflammatory bowel disease

Not specified

Peking Union Medical College Hospital

Patients who underwent FDG PET for suspected or confirmed untreated inflammatory bowel disease will receive and additional FAP-specific PET within two weeks

Characterizing IgG4-RD With 68Ga-FAPI PET/CT

100 patients

10/2021

IgG4-related disease

Not specified

Peking Union Medical College Hospital

Patients who underwent FDG PET for suspected or confirmed untreated IgG4-related disease will receive and additional FAP-specific PET within two weeks

68Ga-FAPI PET/CT in Liver Fibrosis Patients (GFAPILF)

50 patients

12/2023

Liver fibrosis

68Ga -FAPI-04

First Affiliated Hospital of Fujian Medical University

Patients with suspected newly diagnosed or previously treated liver fibrosis will receive FAP-specific PET, transient elastography and blood testing

18F-FDG and 68Ga -FAPI PET/CT in Crohn's Disease

30 patients

09/2021

Crohn’s disease

Not specified

Peking Union Medical College Hospital

Patients with Crohn’s disease with proofs of intestine stricture by other modalities (MRI/CT/ultrasound/endoscopy) will undergo FDG and FAP-specific PET within two days

In patients with resection of the stenotic intestine, the extent of inflammation and fibrosis will be analyzed