Table 3 Diagnostic accuracy of FAR for intraoperative margin assessment of intact WLE specimens compared to histopathology for a high decay corrected [¹⁸F]FDG activity versus a low decay corrected [¹⁸F]FDG activity at time of FAR imaging as well as for the whole study population

Sensitivity

71.4% (29.04–96.33%)

16.7% (0.42–64.12%)

46.2% (19.22–74.87%)

Specificity

71.8% (64.53–78.38%)

90.4% (85.42–94.12%)

81.7 (77.41–85.52%)

PPV

9.3% (5.69–14.71%)

5.0% (0.83–24.88%)

8.1 (4.51–14.15%)

NPV

98.4% (95.07–99.51%)

97.3% (96.15–98.09%)

97.7 (96.32–98.63%)

Overall accuracy

71.8% (64.67–78.25%)

88.2% (83.00–92.31%)

80.5 (76.20–84.36%)