Table 2 Summary of body weights, body weight changes, and food consumption during 14-day treatment-free recovery period
From: Pharmacokinetics, radiation dosimetry, acute toxicity and automated synthesis of [18F]AmBF3-TATE
Group | Dose (mg/kg) | Mean body weight (g) ± SD | Body weight changes (g) ± SD Days 1–14 (n = 5) | Mean food consumption (g) ± SD Days 1–14 (n = 5) | |||
|---|---|---|---|---|---|---|---|
Day 1 (n = 15) | Day 2 (n = 10) | Day 8 (n = 5) | Day 14 (n = 5) | ||||
1-F | 0 | 212.3 ± 11.4 | 197.0 ± 10.9 | 232.4 ± 10.5 | 242.2 ± 13.2 | + 30.2 ± 8.9 | 230.6 ± 15.4 |
2-F | 0.742 | 212.2 ± 13.6 | 195.4 ± 11.3 | 227.1 ± 23.6 | 240.9 ± 19.7 | + 29.3 ± 4.7 | 229.8 ± 16.9 |
1-M | 0 | 295.5 ± 15.0 | 265.8 ± 14.1 | 359.7 ± 14.7 | 403.2 ± 21.1 | + 108.1 ± 14.8 | 404.0 ± 32.3 |
2-M | 0.742 | 297.2 ± 17.2 | 265.4 ± 13.5 | 358.0 ± 21.1 | 388.5 ± 16.1 | + 86.6 ± 11.5* | 365.7 ± 19.4 |