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Fig. 3 | EJNMMI Research

Fig. 3

From: Indium-111-labeled CD166-targeted peptide as a potential nuclear imaging agent for detecting colorectal cancer stem-like cells in a xenograft mouse model

Fig. 3

The protein expressions of cancer stem cell markers and drug resistance in CD166+HCT15 cells. a Four cancer stem cell markers Nanog, c-Myc, OCT4, and Survivin were detected by Western blotting and quantified by densitometry and normalized by GAPDH levels. The data are presented as mean ± SD (n ≥ 3). *P < 0.05, versus CD166HCT15. The arrow indicated the protein position. b The effects of doxorubicin and 5-fluouracil on cell viability. Both CD166+HCT15 and CD166HCT15 cells were treated with doxorubicin and 5-fluouracil (1–50 μM) for 24 h. Data are presented as mean ± SD (n ≥ 5). *P < 0.05, versus CD166HCT15. #P < 0.05, versus Ctrl (control)

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